Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.43 |
| ▸ | GMPS | P49915 | 1/20 | 0.43 |
| ▸ | PI4KA | P42356 | 2/20 | 0.41 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.41 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.41 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.41 |
| ▸ | SLC28A2 | O43868 | 3/20 | 0.41 |
| ▸ | SLC28A1 | O00337 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.41 |
| ▸ | GAPDH | P04406 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | STAT6 | P42226 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13269153 | 0.91 | ADORA2A (0.46) | ADORA2AADORA2BADORA3GMPSPI4KA | |
| SCHEMBL30255364 | 0.89 | SLC28A2 (0.46) | ADORA2AADORA2BADORA3GMPSPI4KA | |
| SCHEMBL1434125 | 0.85 | ADORA3 (0.48) | ADORA2AADORA2BADORA3GMPSPI4KA | |
| SCHEMBL4581732 | 0.82 | ADORA3 (0.49) | ADORA2AADORA2BADORA3GMPSPI4KA | |
| SCHEMBL18047384 | 0.81 | INMT (0.50) | ADORA2AADORA2BADORA3GMPSPI4KA | |
| SCHEMBL2534138 | 0.81 | ADORA3 (0.52) | ADORA2AADORA2BADORA3GMPSPI4KA | |
| SCHEMBL2270714 | 0.81 | ADORA3 (0.54) | ADORA2AADORA2BADORA3GMPSPI4KA | |
| SCHEMBL29639535 | 0.81 | ADORA3 (0.54) | ADORA2AADORA2BADORA3GMPSPI4KA | |
| SCHEMBL10345450 | 0.81 | ADORA3 (0.42) | ADORA2AADORA2BADORA3GMPSPI4KA | |
| SCHEMBL4192535 | 0.81 | ADORA3 (0.48) | ADORA2AADORA2BADORA3GMPSPI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240366627-A1 | SMALL MOLECULES FOR MOUSE SATELLITE CELL PROLIFERATION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2024-11-07 | — | — | US | disclosed |
| US-11963964-B2 | Small molecules for mouse satellite cell proliferation | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2024-04-23 | — | — | US | disclosed |
| US-11426400-B2 | Methods of increasing satellite cell proliferation with vorinostat or bosutinib | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2022-08-30 | — | — | US | disclosed |
| US-20220265282-A1 | USE OF REMOTE ISCHEMIC CONDITIONING FOR TRAUMATIC INJURY | THE HOSPITAL FOR SICK CHILDREN (CA) | 2022-08-25 | — | — | US | disclosed |
| US-20220054499-A1 | SMALL MOLECULES FOR MOUSE SATELLITE CELL PROLIFERATION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2022-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220054499-A1 | SMALL MOLECULES FOR MOUSE SATELLITE CELL PROLIFERATION | MKI67, MYLK2, MYH2 | ADORA2A 3845/4885ADORA2B 4319/4885ADORA3 4225/4885 |
| US-20240366627-A1 | SMALL MOLECULES FOR MOUSE SATELLITE CELL PROLIFERATION | MKI67, MYLK2, MYH2 | ADORA2A 3845/4885ADORA2B 4319/4885ADORA3 4225/4885 |
| US-11963964-B2 | Small molecules for mouse satellite cell proliferation | MKI67, MYLK2, MYH2 | ADORA2A 3845/4885ADORA2B 4319/4885ADORA3 4225/4885 |
| US-11426400-B2 | Methods of increasing satellite cell proliferation with vorinostat or bosutinib | MKI67, CDK4, CDKN1A | ADORA2A 3656/4885ADORA2B 4391/4885ADORA3 4474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.