SCHEMBL29389300

SCHEMBL29389300

Clc1nc(Cl)c2ccccc2n1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.56
MAOB P27338 1/20 0.56
KDM4E B2RXH2 5/20 0.52
ALDH1A1 P00352 4/20 0.52
METAP1 P53582 1/20 0.52
APP P05067 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
PDE5A O76074 1/20 0.50
PDE4A P27815 1/20 0.50
PDE4B Q07343 1/20 0.50
PDE4C Q08493 1/20 0.50
PDE4D Q08499 1/20 0.50
GLA P06280 2/20 0.44
HPGD P15428 2/20 0.44
CASP1 P29466 2/20 0.44
CASP7 P55210 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
HSD17B10 Q99714 2/20 0.44
CHRM2 P08172 1/20 0.44
ADRA2A P08913 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL92707 1.00 MAOA (0.56) MAOAMAOBKDM4EALDH1A1METAP1
Bicarbonate SCHEMBL11023181 0.92 MAOA (0.48) MAOAMAOBKDM4EALDH1A1METAP1
SCHEMBL20319870 0.79 MAOA (0.54) MAOAMAOBKDM4EALDH1A1METAP1
SCHEMBL856788 0.79 TDP1 (0.54) MAOAMAOBKDM4EALDH1A1METAP1
SCHEMBL29461212 0.79 TDP1 (0.54) MAOAMAOBKDM4EALDH1A1METAP1
SCHEMBL29498049 0.79 MAOA (0.39) MAOAMAOBKDM4EALDH1A1METAP1
SCHEMBL28749614 0.79 MAOA (0.39) MAOAMAOBKDM4EALDH1A1METAP1
SCHEMBL17412365 0.78 DHFR (0.51) KDM4EALDH1A1TDP1GLAHPGD
SCHEMBL516091 0.78 TDP1 (0.59) MAOAMAOBKDM4EALDH1A1METAP1
Benzoylenurea SCHEMBL7420432 0.78 PARP1 (0.60) KDM4EALDH1A1TDP1CASP7HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119528886-B Shearing inhibitor for pre-miR-21 post-transcriptional processing and preparation method and application thereof 广东工业大学 2025-04-18 CN claimed
CN-118852128-A Quinazoline derivative containing 2-indolone as well as preparation method and application thereof 成都安博力善生物科技有限公司 2024-10-29 CN claimed
CN-114805223-B 2, 4-disubstituted quinazoline compound for inhibiting EGFR, preparation method and application 自贡市第四人民医院(自贡市急救中心) 2023-05-09 CN claimed
CN-114805223-A 2, 4-disubstituted quinazoline compound for inhibiting EGFR (epidermal growth factor receptor), and preparation method and application thereof 自贡市第四人民医院(自贡市急救中心) 2022-07-29 CN claimed
CN-114763349-B Organic compound, application and preparation method thereof and organic electroluminescent device using same 北京鼎材科技股份有限公司 2026-05-22 CN disclosed
CN-117120423-B Indolylamine 2, 3-dioxygenase inhibitors, methods of preparing the same, and pharmaceutical compositions containing the same 柳韩洋行 2026-02-27 CN disclosed
CN-116003441-B Heteroaromatic derivative regulator, preparation method and application thereof 江苏豪森药业集团有限公司 2025-06-10 CN disclosed
CN-120118071-A Quinazoline compound and application thereof 北京化工大学 2025-06-10 CN disclosed
WO-2025100889-A1 QUINAZOLINE DERIVATIVE, SALT THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT 한국화학연구원 2025-05-15 WO disclosed
CN-119528886-B Shearing inhibitor for pre-miR-21 post-transcriptional processing and preparation method and application thereof 广东工业大学 2025-04-18 CN disclosed
CN-113260615-B Polycyclic compound and organic light-emitting element including the same LT素材株式会社 2025-03-28 CN disclosed
CN-119678675-A Organic electroluminescent device and polymer, composition, mixture and organic compound for preparing the same 浙江光昊光电科技有限公司 2025-03-21 CN disclosed
CN-110330481-B Red phosphorescent compound and organic light-emitting device using same 浙江华显光电科技有限公司 2022-04-08 CN disclosed
CN-114276302-A Method for preparing 2, 4-diamino quinazoline derivative 山东百启生物医药有限公司 2022-04-05 CN disclosed
WO-2022066646-A1 KRAS G12D INHIBITORS Mirati Therapeutics, Inc. (US) 2022-03-31 WO disclosed
CN-108148047-B Compound for organic photoelectric device, composition for organic photoelectric device, and display device 三星SDI株式会社 2022-03-25 CN disclosed
CN-114206841-A CD73 inhibitor 博奥阿迪斯生物科技公司 2022-03-18 CN disclosed
CN-110392682-B Compound, electronic device containing the compound, organic thin-film light-emitting element, display device, and lighting device 东丽株式会社 2022-03-15 CN disclosed
CN-114105976-A Selective ROCK2 kinase inhibitors 杭州邦顺制药有限公司 2022-03-01 CN disclosed
CN-110446711-B Inhibitors of influenza virus replication and uses thereof 广东东阳光药业有限公司 2022-02-15 CN disclosed