Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 17/20 | 0.45 |
| ▸ | RARG | P13631 | 17/20 | 0.45 |
| ▸ | RXRA | P19793 | 5/20 | 0.45 |
| ▸ | RARA | P10276 | 16/20 | 0.41 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7784294 | 0.92 | RARB (0.45) | RARBRARGRXRARARAMAPT | |
| SCHEMBL2910869 | 0.86 | RARB (0.59) | RARBRARGRXRARARACYP26A1 | |
| SCHEMBL7792837 | 0.86 | RARB (0.60) | RARBRARGRXRARARA | |
| SCHEMBL7794287 | 0.86 | RARB (0.60) | RARBRARGRXRARARA | |
| SCHEMBL5847344 | 0.85 | RARB (0.56) | RARBRARGRXRARARACYP26A1 | |
| SCHEMBL7784309 | 0.84 | RARB (0.60) | RARBRARGRXRARARACYP26A1 | |
| SCHEMBL7793751 | 0.78 | RARG (0.58) | RARBRARGRXRARARA | |
| SCHEMBL7792842 | 0.78 | RARG (0.56) | RARBRARGRXRARARA | |
| SCHEMBL7793750 | 0.78 | RARB (0.47) | RARBRARGRXRARARAMAPT | |
| SCHEMBL7793745 | 0.78 | RARB (0.46) | RARBRARGRXRARARAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255543-B1 | USE OF RETINOID-TYPE COMPOUNDS AS ANTIBACTERIAL AGENTS AGAINST STAPHYLOCOCCUS AUREUS | GALDERMA RES & DEV (FR) | 2010-09-01 | — | — | EP | claimed |