Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 15/20 | 0.45 |
| ▸ | RARG | P13631 | 14/20 | 0.45 |
| ▸ | RXRA | P19793 | 4/20 | 0.45 |
| ▸ | RARA | P10276 | 14/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2939205 | 0.92 | RARB (0.45) | RARBRARGRXRARARATDP1 | |
| SCHEMBL5846288 | 0.86 | RARB (0.59) | RARBRARGRXRARARARXRB | |
| SCHEMBL7792837 | 0.86 | RARB (0.60) | RARBRARGRXRARARARXRB | |
| SCHEMBL7794287 | 0.86 | RARB (0.60) | RARBRARGRXRARARARXRB | |
| SCHEMBL5846210 | 0.85 | EGFR (0.52) | RARBRARGRXRARARA | |
| SCHEMBL7784309 | 0.84 | RARB (0.60) | RARBRARGRXRARARARXRB | |
| SCHEMBL9197628 | 0.80 | RARB (0.43) | RARBRARGRXRARARARXRB | |
| SCHEMBL7793751 | 0.78 | RARG (0.58) | RARBRARGRXRARARA | |
| SCHEMBL7792842 | 0.78 | RARG (0.56) | RARBRARGRXRARARARXRB | |
| SCHEMBL7793750 | 0.78 | RARB (0.47) | RARBRARGRXRARARATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0952974-B1 | BIPHENYL DERIVATIVES SUBSTITUTED BY AN AROMATIC OR HETEROAROMATIC RADICAL AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME | GALDERMA RES & DEV (FR) | 2001-11-21 | — | — | EP | claimed |