Known targets — ChEMBL curated mechanism
ACEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2BTKCACNA1CCACNA1DCACNA1FCACNA1SCCR5CPT1BCPT2DPP4DRD1DRD2EGFRERBB2ERBB4HRH1HRH3HTR1AHTR2AHTR2BHTR2CHTR4JAK1JAK2JAK3MPLMTORPPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PPARGSLC6A2SLC6A3SLC6A4SMOTYK2pol
The experimentally established mechanism targets of Setiptiline. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 known ✓ | P21728 | 7/20 | 0.76 |
| ▸ | ADRA2A known ✓ | P08913 | 2/20 | 0.76 |
| ▸ | HTR1A known ✓ | P08908 | 1/20 | 0.76 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.76 |
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.76 |
| ▸ | ADRA1A known ✓ | P35348 | 1/20 | 0.76 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.76 |
| ▸ | DRD2 known ✓ | P14416 | 6/20 | 0.50 |
| ▸ | ADRA2B known ✓ | P18089 | 1/20 | 0.50 |
| ▸ | HTR2A known ✓ | P28223 | 1/20 | 0.50 |
| ▸ | HTR2C known ✓ | P28335 | 1/20 | 0.50 |
| ▸ | HRH1 known ✓ | P35367 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 6/20 | 0.76 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.76 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.76 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.76 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | DRD5 | P21918 | 6/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Setiptiline SCHEMBL623015 | 1.00 | DRD1 (0.76) | DRD1DRD3CHRM2ADRA2ACHRM1 | |
| Setiptiline SCHEMBL29414110 | 0.87 | DRD1 (1.00) | DRD1DRD3CHRM2ADRA2ACHRM1 | |
| Setiptiline SCHEMBL211362 | 0.87 | DRD1 (1.00) | DRD1DRD3CHRM2ADRA2ACHRM1 | |
| Maleic Acid SCHEMBL167958 | 0.81 | DRD2 (0.59) | DRD1DRD3CHRM2ADRA2ACHRM1 | |
| Fumaric Acid SCHEMBL12467794 | 0.81 | DRD2 (0.59) | DRD1DRD3CHRM2ADRA2ACHRM1 | |
| SCHEMBL10728179 | 0.81 | DRD1 (0.86) | DRD1DRD3CHRM2ADRA2ACHRM1 | |
| SCHEMBL10730066 | 0.77 | DRD1 (0.69) | DRD1DRD3CHRM2ADRA2ACHRM1 | |
| Maleic Acid SCHEMBL11488022 | 0.75 | CYP3A4 (0.50) | DRD1DRD3CHRM2ADRA2ACHRM1 | |
| Fumaric Acid SCHEMBL11488028 | 0.75 | CYP3A4 (0.50) | DRD1DRD3CHRM2ADRA2ACHRM1 | |
| SCHEMBL12355565 | 0.73 | DRD1 (0.73) | DRD1DRD3CHRM2ADRA2ACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115223082-B | Aerial video classification method based on space-time multi-scale convertors | 重庆邮电大学 | 2025-06-10 | — | — | CN | disclosed |
| CN-119229319-B | Aerial video classification model and method | 重庆市地理信息和遥感应用中心(重庆市测绘产品质量检验测试中心) | 2025-05-30 | — | — | CN | disclosed |
| CN-119229319-A | Local semantic enhancement encoder, window semantic enhancement transducer block, aerial video classification model and method | 重庆市地理信息和遥感应用中心(重庆市测绘产品质量检验测试中心) | 2024-12-31 | — | — | CN | disclosed |
| WO-2024093624-A1 | MEASUREMENT METHOD AND APPARATUS, AND TERMINAL AND NETWORK DEVICE | 大唐移动通信设备有限公司 | 2024-05-10 | — | — | WO | disclosed |
| US-11916820-B2 | Reference signal configuration, information transmission, and information receiving methods and device | ZTE CORPORATION (CN) | 2024-02-27 | — | — | US | disclosed |
| CN-117542118-A | Unmanned aerial vehicle aerial video action recognition method based on space-time information dynamic modeling | 中国科学技术大学 | 2024-02-09 | — | — | CN | disclosed |
| CN-113573286-B | Method and apparatus for performing device-to-device communication between user devices | SK电信有限公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-116614885-A | Communication method, device, terminal, network equipment and storage medium | 中国移动通信有限公司研究院 | 2023-08-18 | — | — | CN | disclosed |
| CN-108111280-B | Reference signal configuration, information transmission and information receiving method and device | 中兴通讯股份有限公司 | 2023-07-14 | — | — | CN | disclosed |
| US-20230198699-A1 | REFERENCE SIGNAL CONFIGURATION, INFORMATION TRANSMISSION, AND INFORMATION RECEIVING METHODS AND DEVICE | ZTE CORPORATION (CN) | 2023-06-22 | — | — | US | disclosed |
| EP-3595232-B1 | Apparatus and method for transmitting/receiving downlink data channel signal transmission information in cellular radio communication system using cooperative multi-point scheme | SAMSUNG ELECTRONICS CO LTD (KR) | 2023-04-26 | — | — | EP | disclosed |
| CN-114637031-B | Beidou civil dual-frequency satellite-based enhanced message communication method and device | 中国人民解放军32021部队 | 2023-02-28 | — | — | CN | disclosed |
| CN-115223082-A | Aerial video classification method based on space-time multi-scale transform | 重庆邮电大学 | 2022-10-21 | — | — | CN | disclosed |
| CN-112020144-B | Method and equipment for determining resources of asynchronous physical uplink shared channel | 华为技术有限公司 | 2022-09-02 | — | — | CN | disclosed |
| CN-114637031-A | Beidou civil dual-frequency satellite-based enhanced message communication method and device | 中国人民解放军32021部队 | 2022-06-17 | — | — | CN | disclosed |
| US-11337037-B2 | Multicast service reading and sending method, and related device | HUAWEI TECHNOLOGIES CO., LTD (CN) | 2022-05-17 | — | — | US | disclosed |
| CN-109272033-B | Online soft interval kernel learning algorithm based on step length control | 中国石油大学(华东) | 2022-03-08 | — | — | CN | disclosed |