SCHEMBL29396759

SCHEMBL29396759

CCOc1nc(F)cc2nc(S(=O)(=O)Nc3c(Cl)cccc3C(=O)O)nn12

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
WDR5 P61964 1/20 0.39
ACLY P53396 2/20 0.35
CCR2 P41597 2/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
CCR4 P51679 1/20 0.35
CCR5 P51681 1/20 0.35
ALDH1A1 P00352 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL118467 1.00 WDR5 (0.39) WDR5ACLYCCR2CYP1A2CYP3A4
SCHEMBL4890265 1.00 WDR5 (0.39) WDR5ACLYCCR2CYP1A2CYP3A4
SCHEMBL30416435 0.92 CA2 (0.34) WDR5ALDH1A1
SCHEMBL64266 0.92 CA2 (0.34) WDR5ALDH1A1
SCHEMBL22188698 0.91 WDR5 (0.34) WDR5ACLYCCR2CYP1A2CYP3A4
SCHEMBL18643336 0.91 CA2 (0.40) ALDH1A1
Diclosulam SCHEMBL2231960 0.91 CA2 (0.33) WDR5ALDH1A1
SCHEMBL8848603 0.91 WDR5 (0.42) WDR5ALDH1A1
Diclosulam SCHEMBL116344 0.91 GNRHR (0.35) CCR4ALDH1A1SMN1; SMN2
SCHEMBL8848572 0.88 GNRHR (0.34) ACLYCCR4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4519346-A1 SILICONE-POLYETHER COPOLYMER, SEALANTS COMPRISING SAME, AND RELATED METHODS Dow Silicones Corporation (US) 2025-03-12 EP disclosed
CN-119053644-A Silicone-polyether copolymers, sealants comprising silicone-polyether copolymers, and related methods 美国陶氏有机硅公司 2024-11-29 CN disclosed
CN-113195507-B Multifunctional organosilicon compounds and related methods, compounds, and compositions 美国陶氏有机硅公司 2024-09-10 CN disclosed
WO-2023215360-A1 SILICONE-POLYETHER COPOLYMER, SEALANTS COMPRISING SAME, AND RELATED METHODS DOW SILICONES CORPORATION (US) 2023-11-09 WO disclosed
CN-113272364-B Silicone-polyacrylate copolymers, sealants including silicone-polyacrylate copolymers, and related methods 美国陶氏有机硅公司 2023-03-24 CN disclosed
CN-113272363-B Silicone-organic copolymers, sealants including silicone-organic copolymers, and related methods 美国陶氏有机硅公司 2023-02-17 CN disclosed
CN-113272362-B Silicone-polyester copolymers, sealants including silicone-polyester copolymers, and related methods 美国陶氏有机硅公司 2022-06-17 CN disclosed
WO-2022114954-A1 BIOACTIVE COMPLEXES CERADIS PATENT B.V. (NL) 2022-06-02 WO disclosed
CN-113195594-B Silicone-polycarbonate copolymers, sealants including silicone-polycarbonate copolymers, and related methods 美国陶氏有机硅公司 2022-03-29 CN disclosed
CN-110997757-B Isocyanate-functional silicone-polyether copolymers, silicone-polyether-urethane copolymers formed therewith, sealants including the same, and related methods 美国陶氏有机硅公司 2022-03-08 CN disclosed