Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28845790 | 0.79 | KMT2A (0.51) | ALDH1A1POLBKMT2ANPC1RAB9A | |
| SCHEMBL3767288 | 0.74 | CTSK (0.45) | ALDH1A1POLBKMT2ANPC1RAB9A | |
| SCHEMBL29777624 | 0.74 | POLB (0.56) | ALDH1A1POLBNPC1TP53RAB9A | |
| SCHEMBL3766250 | 0.74 | GAA (0.54) | KMT2ANPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL3272690 | 0.73 | FFAR2 (0.41) | KMT2AMEN1 | |
| SCHEMBL3766245 | 0.73 | CHRNB2 (0.41) | POLBNLRP3 | |
| SCHEMBL1609995 | 0.72 | CYP17A1 (0.40) | KMT2ANPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL3768072 | 0.72 | ALDH1A1 (0.37) | ALDH1A1POLBGABRA1GABRG2GABRB3 | |
| SCHEMBL6917924 | 0.71 | ALDH1A1 (0.47) | ALDH1A1POLBKMT2ANPC1RAB9A | |
| SCHEMBL3760987 | 0.71 | POLB (0.56) | ALDH1A1POLBKMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114144410-A | Polyarylurea derivatives and their use in the treatment of muscular diseases | 阿纳格纳斯生物技术股份有限公司 | 2022-03-04 | — | — | CN | disclosed |