Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.56 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.56 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.48 |
| ▸ | GNPAT | O15228 | 2/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPY4R | P50391 | 3/20 | 0.42 |
| ▸ | NPY1R | P25929 | 2/20 | 0.42 |
| ▸ | NPY2R | P49146 | 2/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.42 |
| ▸ | TLR2 | O60603 | 2/20 | 0.42 |
| ▸ | CPA1 | P15085 | 1/20 | 0.41 |
| ▸ | CPA2 | P48052 | 1/20 | 0.41 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.41 |
| ▸ | NMT2 | O60551 | 1/20 | 0.41 |
| ▸ | NMT1 | P30419 | 1/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.40 |
| ▸ | CPB1 | P15086 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29396719 | 1.00 | SIRT6 (0.56) | SIRT6SIRT1SIRT5GNPATFOLH1 | |
| SCHEMBL29396582 | 1.00 | SIRT6 (0.56) | SIRT6SIRT1SIRT5GNPATFOLH1 | |
| SCHEMBL4314204 | 0.95 | SIRT6 (0.54) | SIRT6SIRT1SIRT5GNPATFOLH1 | |
| SCHEMBL4314210 | 0.95 | SIRT6 (0.54) | SIRT6SIRT1SIRT5GNPATFOLH1 | |
| SCHEMBL29655002 | 0.94 | GNPAT (0.53) | SIRT6SIRT1SIRT5GNPATFOLH1 | |
| SCHEMBL1718474 | 0.94 | GNPAT (0.53) | SIRT6SIRT1SIRT5GNPATFOLH1 | |
| SCHEMBL31094973 | 0.94 | GNPAT (0.53) | SIRT6SIRT1SIRT5GNPATFOLH1 | |
| SCHEMBL29454444 | 0.94 | GNPAT (0.53) | SIRT6SIRT1SIRT5GNPATFOLH1 | |
| SCHEMBL29626768 | 0.91 | SIRT6 (0.57) | SIRT6SIRT1SIRT5CA1CA2 | |
| SCHEMBL31024641 | 0.91 | SIRT6 (0.57) | SIRT6SIRT1SIRT5CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4482853-A1 | ANNEXIN A1-DERIVED POLYPEPTIDE ANALOGUES | RESOTHER PHARMA A/S (DK) | 2025-01-01 | — | — | EP | claimed |
| CN-118891273-A | Annexin A1 derived polypeptide analogs | 雷索特制药股份有限公司 | 2024-11-01 | — | — | CN | claimed |
| US-20230303640-A1 | EXENDIN-4 PEPTIDE ANALOGS | TXP PHARMA AG (CH) | 2023-09-28 | — | — | US | claimed |
| US-20230295255-A1 | ANNEXIN A1-DERIVED POLYPEPTIDE ANALOGUES | RESOTHER PHARMA APS (DK) | 2023-09-21 | — | — | US | claimed |
| WO-2023161323-A1 | ANNEXIN A1-DERIVED POLYPEPTIDE ANALOGUES | RESOTHER PHARMA A/S (DK) | 2023-08-31 | — | — | WO | claimed |
| CN-116390938-A | Exendin-4 analogues | TXP制药股份有限公司 | 2023-07-04 | — | — | CN | claimed |
| EP-4200320-A1 | ANNEXIN A1-DERIVED POLYPEPTIDE ANALOGUES | RESOTHER PHARMA A/S (DK) | 2023-06-28 | — | — | EP | claimed |
| EP-4196495-A1 | EXENDIN-4 PEPTIDE ANALOGUES | TXP Pharma GmbH (CH) | 2023-06-21 | — | — | EP | claimed |
| US-20220133839-A1 | PEPTIDE ANALOGUES WITH BRANCHED AMINO ACID PROBE(S) | TXP PHARMA GMBH (CH) | 2022-05-05 | — | — | US | claimed |
| WO-2022034062-A1 | EXENDIN-4 PEPTIDE ANALOGUES | TXP PHARMA AG (CH) | 2022-02-17 | — | — | WO | claimed |
| US-20250388632-A1 | ANNEXIN A1-DERIVED POLYPEPTIDE ANALOGUES | RESOTHER PHARMA AS (DK) | 2025-12-25 | — | — | US | disclosed |
| EP-4482853-A1 | ANNEXIN A1-DERIVED POLYPEPTIDE ANALOGUES | RESOTHER PHARMA A/S (DK) | 2025-01-01 | — | — | EP | disclosed |
| CN-118891273-A | Annexin A1 derived polypeptide analogs | 雷索特制药股份有限公司 | 2024-11-01 | — | — | CN | disclosed |
| US-20230303640-A1 | EXENDIN-4 PEPTIDE ANALOGS | TXP PHARMA AG (CH) | 2023-09-28 | — | — | US | disclosed |
| WO-2023161323-A1 | ANNEXIN A1-DERIVED POLYPEPTIDE ANALOGUES | RESOTHER PHARMA A/S (DK) | 2023-08-31 | — | — | WO | disclosed |
| CN-116390938-A | Exendin-4 analogues | TXP制药股份有限公司 | 2023-07-04 | — | — | CN | disclosed |
| EP-4200320-A1 | ANNEXIN A1-DERIVED POLYPEPTIDE ANALOGUES | RESOTHER PHARMA A/S (DK) | 2023-06-28 | — | — | EP | disclosed |
| EP-4196495-A1 | EXENDIN-4 PEPTIDE ANALOGUES | TXP Pharma GmbH (CH) | 2023-06-21 | — | — | EP | disclosed |
| US-20220133839-A1 | PEPTIDE ANALOGUES WITH BRANCHED AMINO ACID PROBE(S) | TXP PHARMA GMBH (CH) | 2022-05-05 | — | — | US | disclosed |
| WO-2022034062-A1 | EXENDIN-4 PEPTIDE ANALOGUES | TXP PHARMA AG (CH) | 2022-02-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250388632-A1 | ANNEXIN A1-DERIVED POLYPEPTIDE ANALOGUES | ANXA11, ANXA1, ANXA4 | SIRT6 4647/4885SIRT1 4780/4885SIRT5 4691/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.