SCHEMBL29397348

SCHEMBL29397348

O=C(O)C[C@@H]1Cc2ccccc2CN1C(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.48

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.42
FABP5 Q01469 3/20 0.42
FABP7 O15540 2/20 0.42
DPP8 Q6V1X1 1/20 0.41
DPP9 Q86TI2 1/20 0.41
NR1D1 P20393 5/20 0.40
TSHR P16473 1/20 0.38
EPHX2 P34913 1/20 0.38
CASP3 P42574 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL800135 1.00 KMT2A (0.42) KMT2AFABP5FABP7DPP8DPP9
SCHEMBL3365554 1.00 KMT2A (0.42) KMT2AFABP5FABP7DPP8DPP9
SCHEMBL119635 0.84 ACE (0.52) FABP5FABP7
SCHEMBL29398714 0.84 ACE (0.52) FABP5FABP7
SCHEMBL13252698 0.84 ACE (0.52) FABP5FABP7
SCHEMBL119605 0.84 ACE (0.52) FABP5FABP7
SCHEMBL29400546 0.84 ACE (0.52) FABP5FABP7
SCHEMBL23723017 0.80 FFAR1 (0.47) KMT2AFABP5FABP7
SCHEMBL119493 0.80 FFAR1 (0.47) KMT2AFABP5FABP7
SCHEMBL20590863 0.80 FFAR1 (0.47) KMT2AFABP5FABP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260103447-A1 METHODS FOR PREPARING PSMA CONJUGATES ENDOCYTE, INC. 2026-04-16 US disclosed
CN-120965522-B Fmoc-Tea-OH, preparation method thereof and application thereof in polypeptide synthesis 兰树化妆品股份有限公司 2026-02-17 CN disclosed
CN-120965522-B Fmoc-Tea-OH, preparation method thereof and application thereof in polypeptide synthesis 兰树化妆品股份有限公司 2026-02-17 CN disclosed
CN-120965522-A Fmoc-Tea-OH, preparation method thereof and application thereof in polypeptide synthesis 兰树化妆品股份有限公司 2025-11-18 CN disclosed
CN-120965522-A Fmoc-Tea-OH, preparation method thereof and application thereof in polypeptide synthesis 兰树化妆品股份有限公司 2025-11-18 CN disclosed
US-12473265-B2 Methods for preparing PSMA conjugates ENDOCYTE, INC. (US) 2025-11-18 US disclosed
US-12023378-B2 Covalently linked antigen-antibody conjugates HOFFMANN-LA ROCHE INC. (US) 2024-07-02 US disclosed
US-20240010684-A1 MASP INHIBITORY COMPOUNDS AND USES THEREOF BAYER AG (DE) 2024-01-11 US disclosed
US-20230277698-A1 SILICON-CONTAINING LIGAND COMPOUNDS Technische Universität München (DE) 2023-09-07 US disclosed
EP-4185336-A1 SILICON-CONTAINING LIGAND COMPOUNDS Technische Universität München (DE) 2023-05-31 EP disclosed
US-20220220085-A1 METHODS FOR PREPARING PSMA CONJUGATES ENDOCYTE, INC. 2022-07-14 US disclosed
EP-4011904-A1 MASP INHIBITORY COMPOUNDS AND USES THEREOF Bayer Aktiengesellschaft (DE) 2022-06-15 EP disclosed
US-11273223-B2 Bispecific anti-hapten/anti-blood brain barrier receptor antibodies, complexes thereof and their use as blood brain barrier shuttles HOFFMANN-LA ROCHE INC. (US) 2022-03-15 US disclosed
EP-3960768-A1 BISPECIFIC ANTI-HAPTEN/ANTI-BLOOD BRAIN BARRIER RECEPTOR ANTIBODIES, COMPLEXES THEREOF AND THEIR USE AS BLOOD BRAIN BARRIER SHUTTLES F. Hoffmann-La Roche AG (CH) 2022-03-02 EP disclosed
WO-2022018264-A1 SILICON-CONTAINING LIGAND COMPOUNDS Technische Universität München (DE) 2022-01-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260103447-A1 METHODS FOR PREPARING PSMA CONJUGATES PSMA1, PSMA3, PSMA2 KMT2A 2573/4885FABP5 484/4885FABP7 779/4885
US-20220220085-A1 METHODS FOR PREPARING PSMA CONJUGATES FOLH1, PSMA6, PSMA1 KMT2A 1594/4885FABP5 1264/4885FABP7 2152/4885
US-20230277698-A1 SILICON-CONTAINING LIGAND COMPOUNDS KLK3, SHBG, SELPLG KMT2A 2112/4885FABP5 1433/4885FABP7 1744/4885
US-12473265-B2 Methods for preparing PSMA conjugates FOLH1, PSMA6, PSMA1 KMT2A 1594/4885FABP5 1264/4885FABP7 2152/4885
US-20240010684-A1 MASP INHIBITORY COMPOUNDS AND USES THEREOF MASP2, SPINT2, SERPINB1 KMT2A 4666/4885FABP5 1206/4885FABP7 2246/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.