SCHEMBL29398074

SCHEMBL29398074

C#CC[C@@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ MDM4 O15151 3/20 0.57
▸ TP53 P04637 3/20 0.57
▸ CASP3 P42574 2/20 0.52
▸ MDM2 Q00987 5/20 0.49
▸ KMT2A Q03164 2/20 0.49
▸ SLC17A5 Q9NRA2 1/20 0.48
▸ TLR2 O60603 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12493153 1.00 MDM4 (0.57) MDM4TP53CASP3MDM2KMT2A
SCHEMBL29547329 1.00 MDM4 (0.57) MDM4TP53CASP3MDM2KMT2A
SCHEMBL29552281 1.00 MDM4 (0.57) MDM4TP53CASP3MDM2KMT2A
SCHEMBL29400538 1.00 MDM4 (0.57) MDM4TP53CASP3MDM2KMT2A
SCHEMBL30695566 1.00 MDM4 (0.57) MDM4TP53CASP3MDM2KMT2A
SCHEMBL119866 1.00 MDM4 (0.57) MDM4TP53CASP3MDM2KMT2A
SCHEMBL29398455 1.00 MDM4 (0.57) MDM4TP53CASP3MDM2KMT2A
SCHEMBL119859 1.00 MDM4 (0.57) MDM4TP53CASP3MDM2KMT2A
SCHEMBL8656057 0.90 MDM4 (0.59) MDM4TP53CASP3MDM2KMT2A
SCHEMBL14029674 0.89 MDM4 (0.48) MDM4TP53CASP3MDM2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4727654-A1 DLL3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF Mariana Oncology Inc. (US) 2026-04-22 — — EP disclosed
EP-4727653-A1 DLL3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF Mariana Oncology Inc. (US) 2026-04-22 — — EP disclosed
EP-4727655-A1 DLL3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF Mariana Oncology Inc. (US) 2026-04-22 — — EP disclosed
US-20260001924-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME NEW YORK UNIVERSITY (US) 2026-01-01 — — US disclosed
US-20250296959-A1 B7-H3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF MARIANA ONCOLOGY INC (US) 2025-09-25 — — US disclosed
US-12371461-B2 Nemo coiled coil mimics and methods of using same NEW YORK UNIVERSITY (US) 2025-07-29 — — US disclosed
US-20250205373-A1 ENRICHED AND STABLE RADIOLIGAND THERAPY FORMULATIONS AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAME MARIANA ONCOLOGY INC (US) 2025-06-26 — — US disclosed
EP-3303367-B1 STABILIZED MINIMAL COILED-COIL MIMETICS UNIV NEW YORK (US) 2025-06-18 — — EP disclosed
US-20250186541-A1 DLL3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF MARIANA ONCOLOGY INC (US) 2025-06-12 — — US disclosed
WO-2025122615-A1 ENRICHED AND STABLE RADIOLIGAND THERAPY FORMULATIONS AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAME MARIANA ONCOLOGY INC. (US) 2025-06-12 — — WO disclosed
US-20240011979-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS INC. (KR) 2024-01-11 — — US disclosed
WO-2023075435-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE 주식회사 베르티스 2023-05-04 — — WO disclosed
US-20230051872-A1 Multivalent D-Peptidic Compounds for Target Proteins DEXTERA BIOSCIENCES, INC. 2023-02-16 — — US disclosed
US-20220289802-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME CORNELL UNIVERSITY 2022-09-15 — — US disclosed
US-11440938-B2 Stabilized minimal coiled-coil mimetics NEW YORK UNIVERSITY (US) 2022-09-13 — — US disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 — — US disclosed
CN-114989298-A D-peptide compounds against VEGF 反射制药有限公司 2022-09-02 — — CN disclosed
CN-114174334-A D-peptide compounds against VEGF 反射制药有限公司 2022-03-11 — — CN disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 — — WO disclosed
CN-114144433-A Multivalent D-peptide compounds for proteins of interest 反射制药有限公司 2022-03-04 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12371461-B2 Nemo coiled coil mimics and methods of using same COIL, CALCOCO2, NCAPH MDM4 2743/4885TP53 3446/4885CASP3 3773/4885
US-11440938-B2 Stabilized minimal coiled-coil mimetics COIL, CALCOCO2, SMC2 MDM4 256/4885TP53 657/4885CASP3 3879/4885
US-20250186541-A1 DLL3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF DLK1, DBNL, PDLIM5 MDM4 780/4885TP53 109/4885CASP3 2196/4885
US-20250296959-A1 B7-H3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF CD274, CD44, CD74 MDM4 2014/4885TP53 119/4885CASP3 2086/4885
US-20250205373-A1 ENRICHED AND STABLE RADIOLIGAND THERAPY FORMULATIONS AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAME ASGR1, GPR119, LDLR MDM4 1905/4885TP53 42/4885CASP3 4534/4885
US-20230051872-A1 Multivalent D-Peptidic Compounds for Target Proteins PDCD1, PDCD1LG2, CD274 MDM4 167/4885TP53 52/4885CASP3 3601/4885
US-20260001924-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME DDX21, PHAX, RBX1 MDM4 2407/4885TP53 2772/4885CASP3 3274/4885
US-20220289802-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME COIL, CALCOCO2, NCAPH MDM4 2743/4885TP53 3446/4885CASP3 3773/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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