SCHEMBL29398455

SCHEMBL29398455

C#CC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ MDM4 O15151 3/20 0.57
▸ TP53 P04637 3/20 0.57
▸ CASP3 P42574 2/20 0.52
▸ MDM2 Q00987 5/20 0.49
▸ KMT2A Q03164 2/20 0.49
▸ SLC17A5 Q9NRA2 1/20 0.48
▸ TLR2 O60603 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12493153 1.00 MDM4 (0.57) MDM4TP53CASP3MDM2KMT2A
SCHEMBL29547329 1.00 MDM4 (0.57) MDM4TP53CASP3MDM2KMT2A
SCHEMBL29398074 1.00 MDM4 (0.57) MDM4TP53CASP3MDM2KMT2A
SCHEMBL29552281 1.00 MDM4 (0.57) MDM4TP53CASP3MDM2KMT2A
SCHEMBL29400538 1.00 MDM4 (0.57) MDM4TP53CASP3MDM2KMT2A
SCHEMBL30695566 1.00 MDM4 (0.57) MDM4TP53CASP3MDM2KMT2A
SCHEMBL119866 1.00 MDM4 (0.57) MDM4TP53CASP3MDM2KMT2A
SCHEMBL119859 1.00 MDM4 (0.57) MDM4TP53CASP3MDM2KMT2A
SCHEMBL8656057 0.90 MDM4 (0.59) MDM4TP53CASP3MDM2KMT2A
SCHEMBL14029674 0.89 MDM4 (0.48) MDM4TP53CASP3MDM2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114621317-B Activatable multi-modal molecular probe for early diagnosis of prostate cancer and in-vivo longitudinal quantitative research, and preparation method and application thereof 苏州大学 2022-12-30 — — CN claimed
CN-114621317-A Activatable multi-modal molecular probe for early diagnosis of prostate cancer and in-vivo longitudinal quantitative research, and preparation method and application thereof 苏州大学 2022-06-14 — — CN claimed
CN-112961173-B Prostate specific membrane antigen targeted molecular probe, preparation method and application thereof 江南大学附属医院 2022-04-19 — — CN claimed
US-20260137821-A1 PEPTIDE STRUCTURE TARGETING CARBONIC DEHYDROGENASE IX AND USE THEREOF C-BIOMEX CO., LTD. (KR) 2026-05-21 — — US disclosed
US-20260139007-A1 EPHA4 ANTAGONISTS AND USES THEREOF SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INST (US) 2026-05-21 — — US disclosed
EP-4743108-A1 COMPOSITIONS OF PNEUMOCOCCAL ANTIGENS Virometix AG (CH) 2026-05-20 — — EP disclosed
US-20260117070-A1 NEAR-INFRARED FLUORESCENT HEPTAMETHINE DYE CONJUGATES WITH FAVORABLE BLEACHING PROPERTIES HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM GESUNDHEIT & UMWELT GMBH (DE) 2026-04-30 — — US disclosed
US-20260022142-A1 MACROCYCLIC IMMUNOMODULATORS BRISTOL MYERS SQUIBB CO (US) 2026-01-22 — — US disclosed
US-20260007756-A1 COMPOUND AND USE THEREOF COHERENT BIOPHARMA SUZHOU LTD (CN) 2026-01-08 — — US disclosed
EP-3604326-B1 PEPTIDE COMPOUND AND METHOD FOR PRODUCING SAME, COMPOSITION FOR SCREENING USE, AND METHOD FOR SELECTING PEPTIDE COMPOUND FUJIFILM CORP (JP) 2026-01-07 — — EP disclosed
US-20260001924-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME NEW YORK UNIVERSITY (US) 2026-01-01 — — US disclosed
US-20220175761-A1 BI-LIGAND DRUG CONJUGATE AND USE THEREOF COHERENT BIOPHARMA SUZHOU LTD (CN) 2022-06-09 — — US disclosed
CN-111690041-B Polypeptide with anti-tumor activity and preparation method thereof 上海大学 2022-06-07 — — CN disclosed
US-11319347-B2 Peptide compound and method for producing same, composition for screening use, and method for selecting peptide compound FUJIFILM CORPORATION (JP) 2022-05-03 — — US disclosed
CN-107108698-B Macrocyclic peptides as immunomodulators 百时美施贵宝公司 2022-04-29 — — CN disclosed
WO-2022084486-A1 SELF-PURIFIED NUCLEIC ACID ENCODED LIBRARIES ETH ZURICH (CH) 2022-04-28 — — WO disclosed
CN-112961173-B Prostate specific membrane antigen targeted molecular probe, preparation method and application thereof 江南大学附属医院 2022-04-19 — — CN disclosed
US-20220090189-A1 POLYPEPTIDE TAGGED NUCLEOTIDES AND USE THEREOF IN NUCLEIC ACID SEQUENCING BY NANOPORE DETECTION Roche Sequencing Solutions, Inc. (US) 2022-03-24 — — US disclosed
CN-108350017-B Polypeptide-labeled nucleotides and their use in nucleic acid sequencing by nanopore detection 豪夫迈·罗氏有限公司 2022-03-15 — — CN disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220090189-A1 POLYPEPTIDE TAGGED NUCLEOTIDES AND USE THEREOF IN NUCLEIC ACID SEQUENCING BY NANOPORE DETECTION NPPA, ANPEP, TENT4A MDM4 1047/4885TP53 447/4885CASP3 4383/4885
US-20260117070-A1 NEAR-INFRARED FLUORESCENT HEPTAMETHINE DYE CONJUGATES WITH FAVORABLE BLEACHING PROPERTIES CBR1, CBR3, NR2E3 MDM4 4448/4885TP53 4160/4885CASP3 466/4885
US-20260022142-A1 MACROCYCLIC IMMUNOMODULATORS CD274, PDCD1LG2, PDCD1 MDM4 3040/4885TP53 421/4885CASP3 1560/4885
US-20220175761-A1 BI-LIGAND DRUG CONJUGATE AND USE THEREOF SLC10A1, CD47, SELPLG MDM4 4667/4885TP53 1471/4885CASP3 2354/4885
US-20260137821-A1 PEPTIDE STRUCTURE TARGETING CARBONIC DEHYDROGENASE IX AND USE THEREOF CA5A, CA1, CA9 MDM4 4329/4885TP53 2780/4885CASP3 2512/4885
US-20260139007-A1 EPHA4 ANTAGONISTS AND USES THEREOF EPHA4, EPHA1, EPHB4 MDM4 2075/4885TP53 1662/4885CASP3 4081/4885
US-11319347-B2 Peptide compound and method for producing same, composition for screening use, and method for selecting peptide compound VIP, NPPA, NGLY1 MDM4 4154/4885TP53 1409/4885CASP3 2306/4885
US-20260007756-A1 COMPOUND AND USE THEREOF FOLH1, TRPV6, FOLR1 MDM4 3948/4885TP53 1042/4885CASP3 474/4885
US-20260001924-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME DDX21, PHAX, RBX1 MDM4 2407/4885TP53 2772/4885CASP3 3274/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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