Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SENP1 | Q9P0U3 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.31 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2941542 | 0.86 | CNR2 (0.36) | GAAARALDH1A1GFER | |
| SCHEMBL2933992 | 0.79 | MMP3 (0.44) | TSHRLMNAHTTALOX15MEN1 | |
| SCHEMBL2937962 | 0.76 | HRH3 (0.48) | TSHRALOX15 | |
| SCHEMBL2938159 | 0.76 | MEN1 (0.39) | TSHRLMNAHTTALOX15MEN1 | |
| SCHEMBL2939911 | 0.73 | MMP3 (0.47) | TSHRALOX15ARCA2 | |
| SCHEMBL2935347 | 0.70 | ALOX15 (0.46) | TSHRGAALMNAHTTALOX15 | |
| SCHEMBL13799024 | 0.70 | CA2 (0.56) | LMNASENP1MEN1KMT2ANPC1 | |
| SCHEMBL2936698 | 0.70 | ALOX15 (0.46) | TSHRSENP1ALOX15MEN1KMT2A | |
| SCHEMBL2936107 | 0.69 | HSD17B1 (0.48) | TSHRLMNAALOX15NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL2938598 | 0.69 | ALOX15 (0.44) | TSHRSENP1ALOX15MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1494995-B1 | 3-AMINOPHENOL DERIVATIVES SUBSTITUTED IN THE 2-POSITION, AND DYES CONTAINING THESE COMPOUNDS | PROCTER & GAMBLE (US) | 2010-09-22 | — | — | EP | claimed |