SCHEMBL444165

SCHEMBL444165

Clc1ccccc1N=C=Nc1ccccc1Cl

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR3E A5X5Y0 2/20 0.54
HTR3B O95264 2/20 0.54
HTR3A P46098 2/20 0.54
HTR3D Q70Z44 2/20 0.54
HTR3C Q8WXA8 2/20 0.54
LMNA P02545 2/20 0.45
TSHR P16473 2/20 0.45
NPC1 O15118 3/20 0.43
TAAR1 Q96RJ0 1/20 0.42
ESR1 P03372 1/20 0.41
ESR2 Q92731 1/20 0.41
ALDH1A1 P00352 4/20 0.40
MAPT P10636 3/20 0.40
MEN1 O00255 2/20 0.40
RAB9A P51151 2/20 0.40
KMT2A Q03164 2/20 0.40
POLB P06746 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29529229 1.00 HTR3E (0.54) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL27913150 0.91 HTR3E (0.47) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL9741935 0.88 HTR3E (0.48) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL8719167 0.80 HTR3E (0.50) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL93270 0.80 CYP3A4 (0.52) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL29537333 0.80 CYP3A4 (0.52) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL8417246 0.80 S100B (0.46) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL458499 0.80 ALDH1A1 (0.52) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL29401009 0.80 ALDH1A1 (0.52) HTR3EHTR3BHTR3AHTR3DHTR3C
Hydrochloric Acid SCHEMBL9078906 0.78 CYP3A4 (0.50) HTR3EHTR3BHTR3AHTR3DHTR3C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 196 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180134947-A1 METHODS FOR TREATING HIGH TEMPERATURE SUBTERRANEAN FORMATIONS SCHLUMBERGER TECHNOLOGY CORPORATION 2018-05-17 US claimed
WO-2016159817-A1 METHODS FOR TREATING HIGH TEMPERATURE SUBTERRANEAN FORMATIONS SCHLUMBERGER CANADA LIMITED (CA) 2016-10-06 WO claimed
US-8247156-B2 Processes for producing polyester latexes with improved hydrolytic stability XEROX CORPORATION (US) 2012-08-21 US claimed
US-20120064453-A1 PROCESSES FOR PRODUCING POLYESTER LATEXES WITH IMPROVED HYDROLYTIC STABILITY XEROX CORPORATION (US) 2012-03-15 US claimed
US-4012464-A S-(2-diisopropylamino-ethyl)O-ethyl methylphosphonothioate stabilized with soluble carbodiimides THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 1977-03-15 US claimed
US-12559624-B2 Film comprising polylactic acid polymer suitable for graphic articles 3M INNOVATIVE PROPERTIES COMPANY (US) 2026-02-24 US disclosed
US-20240294748-A1 FILM COMPRISING POLYLACTIC ACID POLYMER SUITABLE FOR GRAPHIC ARTICLES 3M INNOVATIVE PROPERTIES COMPANY (US) 2024-09-05 US disclosed
US-12065531-B2 Polyglycolic acid resin and production process thereof PUJING CHEMICAL INDUSTRY CO., LTD. (CN) 2024-08-20 US disclosed
WO-2024143405-A1 METHOD FOR PRODUCING RESIN FOR RECYCLING 花王株式会社 2024-07-04 WO disclosed
CN-116234846-B Resin composition and molded article 株式会社可乐丽 2024-07-02 CN disclosed
EP-4384575-A1 LASER TRANSPARENT COMPOSITION AND MOLDED ARTICLES MADE THEREFROM Celanese International Corporation (US) 2024-06-19 EP disclosed
CN-113574104-B Method for improving tracking resistance of thermoplastic resin 宝理塑料株式会社 2024-06-18 CN disclosed
US-20040242803-A1 Resin composition and molded article, film, and fiber each comprising the same TORAY INDUSTRIES, INC. (JP) 2004-12-02 US disclosed
EP-1445282-A1 RESIN COMPOSITION AND MOLDED ARTICLE FILM AND FIBER EACH COMPRISING THE SAME TORAY INDUSTRIES, INC. (JP) 2004-08-11 EP disclosed
US-5886088-A A BLENDS OF MOLDING MATERIAL COMPRISING AN EPOXY COMPOUND OR RESIN AND A POLYFUNCTIONAL CARBODIIMIDE COMPOUND TO IMPROVE THE MOIST HEAT RESISTANCE, FLUIDITY AND MECHANICAL STRENGTH KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1999-03-23 US disclosed
EP-0764692-A1 POLYETHYLENE TEREPHTHALATE RESIN COMPOSITION KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1997-03-26 EP disclosed
US-4113676-A Aqueous dispersions of esters stabilized with carbodiimides PPG INDUSTRIES, INC. (US) 1978-09-12 US disclosed
US-4012464-A S-(2-diisopropylamino-ethyl)O-ethyl methylphosphonothioate stabilized with soluble carbodiimides THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 1977-03-15 US disclosed
US-4012464-A S-(2-diisopropylamino-ethyl)O-ethyl methylphosphonothioate stabilized with soluble carbodiimides THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 1977-03-15 US disclosed
US-3975329-A HYDROLYTIC AND THERMAL STABILITY THE GOODYEAR TIRE & RUBBER COMPANY (US) 1976-08-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12065531-B2 Polyglycolic acid resin and production process thereof RPN2, RIOX2, RPN1 HTR3E 4016/4885HTR3B 4373/4885HTR3A 4303/4885
US-12559624-B2 Film comprising polylactic acid polymer suitable for graphic articles POT1, PARG, TCP1 HTR3E 2482/4885HTR3B 4179/4885HTR3A 1468/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.