SCHEMBL207554

SCHEMBL207554

S=C=Nc1ccccc1N=C=S

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.62
CYP3A4 P08684 3/20 0.62
HPGD P15428 2/20 0.62
ABCB11 O95342 1/20 0.62
NR3C1 P04150 1/20 0.62
CYP1A2 P05177 1/20 0.62
ADRA2A P08913 1/20 0.62
ADORA3 P0DMS8 1/20 0.62
ALOX15 P16050 1/20 0.62
ADRA2C P18825 1/20 0.62
MAOA P21397 1/20 0.62
DRD1 P21728 1/20 0.62
SLC6A4 P31645 1/20 0.62
HTR2B P41595 1/20 0.62
CCR2 P41597 1/20 0.62
HSD17B10 Q99714 1/20 0.62
TDP1 Q9NUW8 1/20 0.62
MIF P14174 8/20 0.57
POLB P06746 1/20 0.50
APLNR P35414 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29374052 1.00 ALDH1A1 (0.62) ALDH1A1CYP3A4HPGDABCB11NR3C1
SCHEMBL24660121 0.87 ALDH1A1 (0.52) ALDH1A1CYP3A4HPGDABCB11NR3C1
SCHEMBL484005 0.87 CYP3A4 (0.52) ALDH1A1CYP3A4HPGDABCB11NR3C1
SCHEMBL4466979 0.86 ALDH1A1 (0.56) ALDH1A1CYP3A4HPGDABCB11NR3C1
Sulfuric Acid SCHEMBL8443293 0.85 ALDH1A1 (0.55) ALDH1A1CYP3A4HPGDABCB11NR3C1
SCHEMBL348805 0.82 ALDH1A1 (0.52) ALDH1A1CYP3A4HPGDABCB11NR3C1
SCHEMBL1325334 0.82 ALDH1A1 (0.52) ALDH1A1CYP3A4HPGDABCB11NR3C1
SCHEMBL458499 0.82 ALDH1A1 (0.52) ALDH1A1CYP3A4HPGDABCB11NR3C1
SCHEMBL8391915 0.82 L3MBTL1 (0.54) ALDH1A1CYP3A4HPGDABCB11NR3C1
SCHEMBL160878 0.82 ALDH1A1 (0.52) ALDH1A1CYP3A4HPGDABCB11NR3C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1001 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250276100-A1 DEVELOPMENT OF NTSR TARGETED AGENTS FOR IMAGING AND THERAPY APPLICATIONS THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL 2025-09-04 US claimed
CN-119798588-A Polymeric resin and preparation method thereof, optical lens and intelligent glasses 珠海莫界科技有限公司 2025-04-11 CN claimed
EP-4518912-A1 DEVELOPMENT OF NTSR TARGETED AGENTS FOR IMAGING AND THERAPY APPLICATIONS The University of North Carolina at Chapel Hill (US) 2025-03-12 EP claimed
CN-119325393-A Development of agents targeting NTSR for imaging and therapeutic applications 北卡罗来纳大学教堂山分校 2025-01-17 CN claimed
WO-2023215778-A1 DEVELOPMENT OF NTSR TARGETED AGENTS FOR IMAGING AND THERAPY APPLICATIONS THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2023-11-09 WO claimed
US-20220333168-A1 METHOD FOR IDENTIFYING AND QUANTIFYING ORGANIC AND BIOCHEMICAL SUBSTANCES Roswell Biotechnologies, Inc. (US) 2022-10-20 US claimed
CN-113580099-B Coding type nanometer machine and control and preparation method thereof 东南大学 2022-10-14 CN claimed
CN-113580099-A Coding type nanometer machine and control and preparation method thereof 东南大学 2021-11-02 CN claimed
US-20200165667-A1 METHOD FOR IDENTIFYING AND QUANTIFYING ORGANIC AND BIOCHEMICAL SUBSTANCES Roswell ME Inc. 2020-05-28 US claimed
CN-105143300-B The manufacture method of polymerizable composition for optical material, optical material and optical material 三井化学株式会社 2017-11-24 CN claimed
US-6287824-B1 AMPLIFICATION IS RAPID AND EFFICIENT SINCE IT INVOLVES A SINGLE ISOTHERMIC REACTION THAT REPLICATES THE VECTOR SEQUENCES EXPONENTIALLY YALE UNIVERSITY 2001-09-11 US claimed
EP-1114184-A2 MOLECULAR CLONING USING ROLLING CIRCLE AMPLIFICATION YALE UNIVERSITY (US) 2001-07-11 EP claimed
WO-2001046214-A2 COMPOUND COMPRISING A NUCLEIC ACID MOIETY AND AN ORGANO-SILANE MOIETY VBC-GENOMICS BIOSCIENCE RESEARCH GMBH (AT) 2001-06-28 WO claimed
WO-2001046213-A2 COMPOUND COMPRISING A PEPTIDE MOIETY AND AN ORGANO-SILANE MOIETY. VBC-GENOMICS BIOSCIENCE RESEARCH GMBH (AT) 2001-06-28 WO claimed
WO-2000029373-A2 DERIVATISATION OF SUPPORT SURFACES Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) 2000-05-25 WO claimed
WO-2000015779-A2 MOLECULAR CLONING USING ROLLING CIRCLE AMPLIFICATION YALE UNIVERSITY (US) 2000-03-23 WO claimed
WO-1999028505-A1 METHODS AND DEVICES FOR MEASURING DIFFERENTIAL GENE EXPRESSION CURAGEN CORPORATION (US) 1999-06-10 WO claimed
EP-0816364-A1 Reagents for lysergic acid diethylamide immunoassay F. HOFFMANN-LA ROCHE AG (CH) 1998-01-07 EP claimed
US-4650769-A Microcapsules for immune response FUJI PHOTO FILM CO., LTD. (JP) 1987-03-17 US claimed
US-4584103-A REACTING WITH HYDROXYLAMINE, THEN DIFUNCTIONAL COMPOUND AND COMPOUND CONTAINING IONIZABLE GROUP ALIGENA AG (CH) 1986-04-22 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250276100-A1 DEVELOPMENT OF NTSR TARGETED AGENTS FOR IMAGING AND THERAPY APPLICATIONS NTSR1, NTSR2, NPSR1 ALDH1A1 4663/4885CYP3A4 4731/4885HPGD 3325/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.