SCHEMBL29401050

SCHEMBL29401050

O=C(O)[C@@H]1CC2CCCCC2N1C(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ACE P12821 7/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
USP2 O75604 1/20 0.45
LMNA P02545 1/20 0.45
FABP5 Q01469 3/20 0.44
FABP7 O15540 2/20 0.44
CYP3A4 P08684 1/20 0.43
ALOX15 P16050 1/20 0.43
FFAR2 O15552 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28944303 1.00 ACE (0.45) ACEMEN1KMT2AUSP2LMNA
SCHEMBL22636129 1.00 ACE (0.45) ACEMEN1KMT2AUSP2LMNA
SCHEMBL800319 1.00 ACE (0.45) ACEMEN1KMT2AUSP2LMNA
SCHEMBL4802204 1.00 ACE (0.45) ACEMEN1KMT2AUSP2LMNA
SCHEMBL29634909 1.00 ACE (0.45) ACEMEN1KMT2AUSP2LMNA
SCHEMBL30532495 1.00 ACE (0.45) ACEMEN1KMT2AUSP2LMNA
SCHEMBL29779377 1.00 ACE (0.45) ACEMEN1KMT2AUSP2LMNA
SCHEMBL3308417 0.98 ACE (0.45) ACEMEN1KMT2AUSP2LMNA
SCHEMBL22648502 0.98 ACE (0.45) ACEMEN1KMT2AUSP2LMNA
SCHEMBL17356388 0.98 ACE (0.45) ACEMEN1KMT2AUSP2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110776558-B Method for solid-phase synthesis of actibant acetate 江苏豪森药业集团有限公司 2023-08-11 CN claimed
CN-111944016-B Preparation method of icatibant acetate 台州吉诺生物科技有限公司 2022-04-29 CN claimed
EP-4695268-A1 ANTIBACTERIAL COVALENT PEPTIDE INHIBITORS Université de Bordeaux (FR) 2026-02-18 EP disclosed
EP-3966226-B1 MASP INHIBITORY COMPOUNDS AND USES THEREOF BAYER AG (DE) 2025-12-24 EP disclosed
US-12503491-B2 MASP inhibitory compounds and uses thereof BAYER AKTIENGESELLSCHAFT (DE) 2025-12-23 US disclosed
EP-3650464-B1 PEPTIDE COMPOUND AND APPLICATION THEREOF, AND COMPOSITION CONTAINING PEPTIDE COMPOUND SHANGPHARMA INNOVATION INC (US) 2025-11-05 EP disclosed
US-12371454-B2 Cyclic peptide compound having Kras inhibitory action CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-07-29 US disclosed
CN-114585637-B MASP-inhibitory compounds and uses thereof 拜耳公司 2025-04-15 CN disclosed
US-20240400617-A1 CYCLIC PEPTIDE COMPOUND HAVING KRAS INHIBITORY ACTION CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2024-12-05 US disclosed
US-20240368215-A1 METHOD AND APPARATUS FOR PRODUCING PEPTIDE YOKOGAWA ELECTRIC CORPORATION (JP) 2024-11-07 US disclosed
EP-4458460-A1 METHOD AND APPARATUS FOR PRODUCING PEPTIDE Yokogawa Electric Corporation (JP) 2024-11-06 EP disclosed
US-11427615-B2 Peptide compound and application thereof, and composition containing peptide compound XDCEXPLORER (SHANGHAI) CO., LTD. (CN) 2022-08-30 US disclosed
US-11420997-B2 Peptide synthesis method JITSUBO CO., LTD. 2022-08-23 US disclosed
EP-4011904-A1 MASP INHIBITORY COMPOUNDS AND USES THEREOF Bayer Aktiengesellschaft (DE) 2022-06-15 EP disclosed
CN-114585637-A MASP inhibiting compounds and uses thereof 拜耳公司 2022-06-03 CN disclosed
WO-2022096394-A1 MASP INHIBITORY COMPOUNDS AND USES THEREOF BAYER AKTIENGESELLSCHAFT (DE) 2022-05-12 WO disclosed
CN-111944016-B Preparation method of icatibant acetate 台州吉诺生物科技有限公司 2022-04-29 CN disclosed
EP-3966226-A1 MASP INHIBITORY COMPOUNDS AND USES THEREOF Bayer Aktiengesellschaft (DE) 2022-03-16 EP disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 WO disclosed
US-20220050107-A1 NOVEL ACTIVITY-BASED PROBES FOR NEUTROPHIL ELASTASE AND THEIR USE TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2022-02-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12503491-B2 MASP inhibitory compounds and uses thereof MASP2, SERPINB1, SPINT2 ACE 22/4885MEN1 537/4885KMT2A 4690/4885
US-11427615-B2 Peptide compound and application thereof, and composition containing peptide compound KISS1R, VIP, NPY1R ACE 1694/4885MEN1 268/4885KMT2A 3979/4885
US-20240368215-A1 METHOD AND APPARATUS FOR PRODUCING PEPTIDE VIP, ANPEP, NPPA ACE 380/4885MEN1 1967/4885KMT2A 3997/4885
US-20240400617-A1 CYCLIC PEPTIDE COMPOUND HAVING KRAS INHIBITORY ACTION KRAS, NRAS, HRAS ACE 831/4885MEN1 492/4885KMT2A 3145/4885
US-11420997-B2 Peptide synthesis method NPPA, ANPEP, VIP ACE 824/4885MEN1 1827/4885KMT2A 3246/4885
US-12371454-B2 Cyclic peptide compound having Kras inhibitory action KRAS, NRAS, HRAS ACE 831/4885MEN1 492/4885KMT2A 3145/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.