SCHEMBL29369342

SCHEMBL29369342

O=c1oc2cc(O)ccc2c2cc(O)c(O)cc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKLR P30613 2/20 1.00
PDE2A O00408 1/20 0.79
NPSR1 Q6W5P4 1/20 0.69
RXFP1 Q9HBX9 1/20 0.69
MAPT P10636 3/20 0.62
KDM4E B2RXH2 4/20 0.61
ALDH1A1 P00352 4/20 0.61
LMNA P02545 2/20 0.61
HSD17B10 Q99714 2/20 0.61
ALOX15 P16050 1/20 0.61
HTT P42858 1/20 0.61
SMN1; SMN2 Q16637 1/20 0.61
HSD17B3 P37058 3/20 0.61
ESR1 P03372 4/20 0.59
ESR2 Q92731 4/20 0.59
KMT2A Q03164 2/20 0.58
GLA P06280 2/20 0.57
GAA P10253 2/20 0.57
HPGD P15428 2/20 0.57
MAOA P21397 2/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15423100 1.00 PKLR (1.00) PKLRPDE2ANPSR1RXFP1MAPT
SCHEMBL14294225 0.93 PKLR (0.87) PKLRPDE2ANPSR1RXFP1MAPT
SCHEMBL16663940 0.89 PDE2A (0.85) PKLRPDE2ANPSR1RXFP1MAPT
SCHEMBL803408 0.89 PDE2A (1.00) PKLRPDE2ANPSR1RXFP1MAPT
SCHEMBL29368885 0.89 PDE2A (1.00) PKLRPDE2ANPSR1RXFP1MAPT
SCHEMBL29401099 0.89 PDE2A (1.00) PKLRPDE2ANPSR1RXFP1MAPT
SCHEMBL26772728 0.89 PKLR (0.79) PKLRPDE2ANPSR1RXFP1MAPT
SCHEMBL26772481 0.89 PKLR (0.79) PKLRPDE2ANPSR1RXFP1MAPT
SCHEMBL26772733 0.89 PKLR (0.79) PKLRPDE2ANPSR1RXFP1MAPT
SCHEMBL26768208 0.89 PKLR (0.79) PKLRPDE2ANPSR1RXFP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 369 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026104588-A1 UROLITHIN COMBINATION AMAZENTIS SA (CH) 2026-05-21 WO claimed
US-12605360-B2 Compositions and methods using xanthan gum to stabilize at least one urolithin in an aqueous matrix SOCIETE DES PRODUITS NESTLE S.A. (CH) 2026-04-21 US claimed
US-20260090966-A1 UROLITHIN COMPOSITIONS AMAZENTIS SA (CH) 2026-04-02 US claimed
EP-4712785-A1 CHEWABLE COMPOSITIONS COMPRISING PECTIN AND UROLITHIN Amazentis SA (CH) 2026-03-25 EP claimed
US-20260069693-A1 UROLITHINS AND T-CELL MEDIATED IMMUNE RESPONSE CHEMOTHERAPEUTISCHES FORSCHUNGSINSTITUT GEORG SPEYER HAUS (DE) 2026-03-12 US claimed
US-20250375414-A1 UROLITHIN COMBINATIONS AMAZENTIS SA (CH) 2025-12-11 US claimed
US-20250375415-A1 ENHANCING AUTOPHAGY OR INCREASING LONGEVITY BY ADMINISTRATION OF UROLITHINS AMAZENTIS SA (CH) 2025-12-11 US claimed
US-20250367159-A1 UROLITHIN GUMMY (PECTIN) FORMULATIONS AMAZENTIS SA (CH) 2025-12-04 US claimed
US-20250367099-A1 UROLITHIN COMBINATIONS DAMICO DAVIDE (CH) 2025-12-04 US claimed
EP-4395771-B1 TREATING LONG COVID-19 WITH UROLITHINS AMAZENTIS SA (CH) 2025-11-19 EP claimed
US-20220267741-A1 ENZYME CAPABLE OF DEHYDROXYLATING HYDROXYL GROUP IN UROLITHIN COMPOUND DAICEL CORPORATION (JP) 2022-08-25 US claimed
EP-3561067-B1 METHOD FOR PRODUCING UROLITHINS DAICEL CORP (JP) 2022-08-03 EP claimed
CN-114760996-A Direct AMPK activator compounds in combination with indirect AMPK activator compounds, compositions, methods, and uses thereof 雀巢产品有限公司 2022-07-15 CN claimed
WO-2022115863-A1 CHROMIUM ALLOY COATED NUCLEAR FUEL RODS WESTINGHOUSE ELECTRIC COMPANY LLC (US) 2022-06-02 WO claimed
EP-4006163-A1 ENZYME CAPABLE OF DEHYDROXYLATING HYDROXYL GROUP IN UROLITHIN COMPOUND Daicel Corporation (JP) 2022-06-01 EP claimed
US-20220105117-A1 COMPOSITIONS COMPRISING NICOTINAMIDE RIBOSIDE AND A UROLITHIN AMAZENTIS SA (CH) 2022-04-07 US claimed
WO-2022063846-A1 COMPOSITIONS AND METHODS USING XANTHAN GUM TO STABILIZE AT LEAST ONE UROLITHIN IN AN AQUEOUS MATRIX Société des Produits Nestlé S.A. (CH) 2022-03-31 WO claimed
US-20220096433-A1 COMPOSITIONS COMPRISING UROLITHINS AND USES THEREOF FOR THE STIMULATION OF INSULIN SECRETION CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2022-03-31 US claimed
CN-114041531-A Ellagic acid feed additive and application thereof 中国农业大学 2022-02-15 CN claimed
US-20220044830-A1 COATED FUEL PELLETS, METHODS OF MAKING AND USING SAME UCHICAGO ARGONNE, LLC 2022-02-10 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260090966-A1 UROLITHIN COMPOSITIONS UTS2R, TAS2R30, TAS2R42 PKLR 4699/4885PDE2A 688/4885NPSR1 3978/4885
US-20260069693-A1 UROLITHINS AND T-CELL MEDIATED IMMUNE RESPONSE MAVS, TFAM, MCU PKLR 3874/4885PDE2A 4316/4885NPSR1 3647/4885
US-20250375414-A1 UROLITHIN COMBINATIONS AHCY, BHMT, BHMT2 PKLR 3073/4885PDE2A 1581/4885NPSR1 3769/4885
US-20220105117-A1 COMPOSITIONS COMPRISING NICOTINAMIDE RIBOSIDE AND A UROLITHIN NNT, UQCRC1, UQCRC2 PKLR 2582/4885PDE2A 2684/4885NPSR1 3567/4885
US-20250367099-A1 UROLITHIN COMBINATIONS ASAH2, HEXB, SGMS2 PKLR 478/4885PDE2A 2314/4885NPSR1 3018/4885
US-20250367159-A1 UROLITHIN GUMMY (PECTIN) FORMULATIONS PYGM, GALE, GYS1 PKLR 537/4885PDE2A 265/4885NPSR1 4548/4885
US-20250375415-A1 ENHANCING AUTOPHAGY OR INCREASING LONGEVITY BY ADMINISTRATION OF UROLITHINS ATG7, BECN1, ATG4A PKLR 2562/4885PDE2A 2005/4885NPSR1 4309/4885
US-12605360-B2 Compositions and methods using xanthan gum to stabilize at least one urolithin in an aqueous matrix LGALS9, PLAU, TAS2R19 PKLR 1846/4885PDE2A 772/4885NPSR1 4851/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.