SCHEMBL29401352

SCHEMBL29401352

CCOC(=O)[C@@H](NC(C)=O)c1ccc(O)cc1

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.47
CA12 O43570 3/20 0.46
CA1 P00915 3/20 0.46
CA2 P00918 3/20 0.46
CA9 Q16790 3/20 0.46
ESR1 P03372 2/20 0.46
ESR2 Q92731 2/20 0.46
CA7 P43166 2/20 0.46
CA14 Q9ULX7 2/20 0.46
ACACB O00763 6/20 0.43
KMT2A Q03164 1/20 0.43
ACACA Q13085 1/20 0.43
MAPK1 P28482 1/20 0.41
ALDH1A1 P00352 1/20 0.41
TSHR P16473 1/20 0.41
FOLH1 Q04609 1/20 0.40
MIF P14174 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16245315 1.00 LMNA (0.48) LMNASMN1; SMN2CA12CA1CA2
SCHEMBL16263469 1.00 LMNA (0.48) LMNASMN1; SMN2CA12CA1CA2
SCHEMBL11841853 0.85 SMN1; SMN2 (0.62) LMNASMN1; SMN2KMT2A
SCHEMBL30079260 0.85 ESR1 (0.50) CA12CA1CA2CA9ESR1
SCHEMBL2684484 0.84 SMN1; SMN2 (0.48) LMNASMN1; SMN2CA12CA1CA2
SCHEMBL34473818 0.82 ALDH1A1 (0.50) LMNAACACBACACAALDH1A1
SCHEMBL16245369 0.81 SMN1; SMN2 (0.51) LMNASMN1; SMN2CA12CA1CA2
SCHEMBL16244682 0.81 CTSS (0.48) LMNASMN1; SMN2CA12CA1CA2
SCHEMBL1826234 0.80 ACACB (0.44) LMNASMN1; SMN2CA12CA1CA2
SCHEMBL11693549 0.78 FOLH1 (0.56) CA12CA1CA2CA9ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 EP disclosed
US-20240011979-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS INC. (KR) 2024-01-11 US disclosed
CN-116829949-A Compositions for detecting or measuring analytes 伯蒂斯有限公司 2023-09-29 CN disclosed
WO-2023075435-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE 주식회사 베르티스 2023-05-04 WO disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 US disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 WO disclosed