Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH5 | Q6P6C2 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3835955 | 0.78 | ALDH1A1 (0.39) | ALKBH5KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL1114873 | 0.77 | HSP90AA1 (0.46) | KMT2AALDH1A1GAACYP3A4NPC1 | |
| SCHEMBL3264283 | 0.77 | ALDH1A1 (0.50) | KMT2AMEN1ALDH1A1MAPTGAA | |
| SCHEMBL10373240 | 0.75 | MAPT (0.61) | KMT2AMEN1ALDH1A1MAPTGAA | |
| SCHEMBL407942 | 0.74 | ALKBH5 (0.64) | ALKBH5KMT2AMEN1HCAR1ALDH1A1 | |
| SCHEMBL6863454 | 0.74 | ALKBH5 (0.55) | ALKBH5KMT2AMEN1HCAR1ALDH1A1 | |
| SCHEMBL3262746 | 0.74 | NPC1 (0.42) | ALKBH5KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL3262867 | 0.73 | ALKBH5 (0.54) | ALKBH5KMT2AMEN1ALDH1A1ADRB1 | |
| SCHEMBL10373537 | 0.73 | MAPT (0.50) | KMT2AMEN1ALDH1A1HPGDADRB1 | |
| SCHEMBL4334784 | 0.70 | SMN1; SMN2 (0.53) | ALKBH5KMT2AMEN1HCAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112645879-B | Method for synthesizing Eltrombopag by using microchannel reactor | 上药康丽（常州）药业有限公司 | 2022-03-11 | — | — | CN | claimed |
| CN-112645879-B | Method for synthesizing Eltrombopag by using microchannel reactor | 上药康丽（常州）药业有限公司 | 2022-03-11 | — | — | CN | disclosed |