Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.54 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | TYMP | P19971 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10373240 | 0.83 | MAPT (0.61) | MGLLMEN1KMT2ARAB9AL3MBTL1 | |
| SCHEMBL3264283 | 0.79 | ALDH1A1 (0.50) | MEN1KMT2ANPC1RAB9AL3MBTL1 | |
| SCHEMBL3262746 | 0.79 | NPC1 (0.42) | ALKBH5MEN1KMT2ANPC1RAB9A | |
| SCHEMBL486408 | 0.77 | MAPT (0.71) | ALKBH5MGLLCYP1A2MEN1KMT2A | |
| SCHEMBL28011551 | 0.76 | TP53 (0.49) | ALKBH5MGLLCYP1A2MEN1KMT2A | |
| SCHEMBL1114873 | 0.75 | HSP90AA1 (0.46) | CYP1A2KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL29401773 | 0.73 | ALKBH5 (0.51) | ALKBH5CYP1A2MEN1KMT2ANPC1 | |
| SCHEMBL3268349 | 0.71 | CYP2E1 (0.46) | MEN1KMT2ANPC1RAB9AL3MBTL1 | |
| SCHEMBL16719288 | 0.70 | NOTUM (0.57) | MGLLCYP1A2MEN1KMT2ANPC1 | |
| SCHEMBL3835955 | 0.69 | ALDH1A1 (0.39) | ALKBH5MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015657-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| WO-2010015657-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| EP-2151433-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |
| EP-2151433-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |