SCHEMBL9014074

SCHEMBL9014074

CCN(CC)c1ccc2c(C)c[nH]c2c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S100B P04271 1/20 0.47
AR P10275 3/20 0.46
ALDH1A1 P00352 8/20 0.45
L3MBTL1 Q9Y468 4/20 0.45
CYP3A4 P08684 4/20 0.45
ATM Q13315 3/20 0.45
HPGD P15428 3/20 0.45
MAPK1 P28482 3/20 0.45
GLA P06280 3/20 0.45
IGLV6-57 P01721 3/20 0.45
HSD17B10 Q99714 2/20 0.45
CASP1 P29466 1/20 0.45
CASP7 P55210 1/20 0.45
HIF1A Q16665 1/20 0.45
TERT O14746 1/20 0.41
HTR1A P08908 1/20 0.40
KDM4E B2RXH2 3/20 0.39
TDP1 Q9NUW8 3/20 0.39
HTT P42858 1/20 0.39
MAPT P10636 4/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8297204 0.80 ATM (0.48) ARALDH1A1L3MBTL1ATMHPGD
SCHEMBL29402764 0.77 AR (0.69) ARALDH1A1L3MBTL1CYP3A4ATM
SCHEMBL22501754 0.77 AR (0.69) ARALDH1A1L3MBTL1CYP3A4ATM
SCHEMBL8599686 0.73 AR (0.43) S100BARALDH1A1L3MBTL1CYP3A4
SCHEMBL9001660 0.73 KIF11 (0.49) ATMHTR1A
SCHEMBL4031293 0.72 GPR84 (0.58) ATMHTR1A
SCHEMBL12352 0.71 ATM (0.56) ATMHSD17B10KDM4EMEN1KMT2A
SCHEMBL29555842 0.71 ATM (0.56) ATMHSD17B10KDM4EMEN1KMT2A
SCHEMBL8291070 0.69 ALDH1A1 (0.47) ALDH1A1ATMHPGDHSD17B10KDM4E
SCHEMBL4300627 0.69 S100B (0.67) S100BALDH1A1L3MBTL1CYP3A4ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0540468-B1 NIR-dyes, method for their preparation and their use CIBA GEIGY AG (CH) 1996-12-04 EP disclosed
US-5391762-A Near infra red absorbers for optical recording media CIBA-GEIGY CORPORATION (US) 1995-02-21 US disclosed
US-5266699-A Near infrared radiation absorbers; optical recording media CIBA-GEIGY CORPORATION (US) 1993-11-30 US disclosed
EP-0540468-A1 NIR-dyes, method for their preparation and their use CIBA-GEIGY AG (CH) 1993-05-05 EP disclosed