Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2B | Q14289 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | CDC25B | P30305 | 1/20 | 0.49 |
| ▸ | ACLY | P53396 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL940353 | 1.00 | PTK2B (0.58) | PTK2BSMN1; SMN2CDC25BACLYTDP1 | |
| SCHEMBL5030349 | 0.87 | PTK2B (0.44) | PTK2BSMN1; SMN2ACLYLMNAMAPK1 | |
| SCHEMBL940704 | 0.85 | PTK2B (0.43) | PTK2BSMN1; SMN2ACLYLMNATSHR | |
| SCHEMBL3160473 | 0.85 | LMNA (0.47) | PTK2BSMN1; SMN2CDC25BACLYTDP1 | |
| SCHEMBL11597913 | 0.84 | PTK2B (0.42) | PTK2BSMN1; SMN2RAB9ALMNAKMT2A | |
| SCHEMBL2593426 | 0.81 | PTK2B (0.58) | PTK2BSMN1; SMN2CDC25BACLYTDP1 | |
| SCHEMBL941191 | 0.81 | PKM (0.58) | PTK2BSMN1; SMN2CDC25BACLYTDP1 | |
| Hydrochloric Acid SCHEMBL11169517 | 0.80 | PKM (0.57) | PTK2BSMN1; SMN2CDC25BACLYTDP1 | |
| SCHEMBL19475371 | 0.80 | ACLY (0.51) | PTK2BSMN1; SMN2ACLYKMT2APKM | |
| SCHEMBL30695462 | 0.80 | ACLY (0.51) | PTK2BSMN1; SMN2ACLYKMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114174259-A | Modulators of intracellular chloride concentration | 意大利学院科技基金会 | 2022-03-11 | — | — | CN | disclosed |