Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 12/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | NEK2 | P51955 | 1/20 | 0.44 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | INSR | P06213 | 2/20 | 0.43 |
| ▸ | EP300 | Q09472 | 1/20 | 0.43 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.43 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | RET | P07949 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11895869 | 1.00 | NFE2L2 (0.53) | NFE2L2KDM4ECHEK1NEK2LIMK1 | |
| SCHEMBL11895872 | 1.00 | NFE2L2 (0.53) | NFE2L2KDM4ECHEK1NEK2LIMK1 | |
| SCHEMBL9915625 | 0.88 | CHEK1 (0.55) | KDM4ECHEK1NEK2LIMK1DYRK1A | |
| SCHEMBL13284469 | 0.79 | CHEK1 (0.50) | KDM4ECHEK1NEK2LIMK1DYRK1A | |
| SCHEMBL8699190 | 0.77 | RET (0.40) | KDM4ECHEK1NEK2LIMK1DYRK1A | |
| SCHEMBL9393214 | 0.75 | INSR (0.47) | NFE2L2KDM4ECHEK1NEK2LIMK1 | |
| SCHEMBL13759864 | 0.75 | CHEK1 (0.46) | KDM4ECHEK1NEK2LIMK1DYRK1A | |
| SCHEMBL28048773 | 0.74 | MAPT (0.60) | CHEK1NEK2LIMK1DYRK1ACLK4 | |
| SCHEMBL16070373 | 0.74 | NPC1 (0.50) | KDM4ECHEK1NEK2LIMK1DYRK1A | |
| SCHEMBL9314848 | 0.74 | CHEK1 (0.57) | KDM4ECHEK1NEK2LIMK1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110015962-B | Stilbene analogs and methods of treating cancer | 肯塔基大学研究基金会 | 2022-03-15 | — | — | CN | disclosed |