Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.48 |
| ▸ | NTRK1 | P04629 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NAMPT | P43490 | 3/20 | 0.42 |
| ▸ | ABL1 | P00519 | 6/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | BCR | P11274 | 3/20 | 0.41 |
| ▸ | ESYT2 | A0FGR8 | 1/20 | 0.41 |
| ▸ | PLEKHG3 | A1L390 | 1/20 | 0.41 |
| ▸ | NBAS | A2RRP1 | 1/20 | 0.41 |
| ▸ | CNOT1 | A5YKK6 | 1/20 | 0.41 |
| ▸ | TBKBP1 | A7MCY6 | 1/20 | 0.41 |
| ▸ | MYO1G | B0I1T2 | 1/20 | 0.41 |
| ▸ | AGPS | O00116 | 1/20 | 0.41 |
| ▸ | MYO1F | O00160 | 1/20 | 0.41 |
| ▸ | SNAP23 | O00161 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22659854 | 1.00 | KCNT1 (0.48) | KCNT1NTRK1LMNANAMPTABL1 | |
| SCHEMBL29406420 | 0.91 | NTRK1 (0.47) | NTRK1LMNABRAFMAPK14 | |
| SCHEMBL24571213 | 0.91 | NTRK1 (0.47) | NTRK1LMNABRAFMAPK14 | |
| SCHEMBL24571216 | 0.90 | KCNT1 (0.46) | KCNT1NTRK1EGFRPDGFRBPDGFRA | |
| SCHEMBL22659319 | 0.89 | HPGDS (0.42) | KCNT1NTRK1IGF1RBRAFDYRK1A | |
| SCHEMBL29405919 | 0.89 | HPGDS (0.42) | KCNT1NTRK1IGF1RBRAFDYRK1A | |
| SCHEMBL22659317 | 0.88 | KCNT1 (0.47) | KCNT1NTRK1LMNAABL1PDGFRB | |
| SCHEMBL22659076 | 0.87 | WDR5 (0.45) | KCNT1NTRK1BRAFWDR5MAPK14 | |
| SCHEMBL22659822 | 0.87 | LCK (0.45) | LMNALCKPARP1BRAFATM | |
| SCHEMBL22659814 | 0.86 | STIM1 (0.44) | KCNT1NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3966208-A2 | COMPOUNDS AND METHODS FOR TREATING CANCER | Antidote IP Holdings, LLC (US) | 2022-03-16 | — | — | EP | disclosed |