Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | AHR | P35869 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL787558 | 0.92 | ALOX5 (0.54) | ALOX5DRD4AHRKDM4ECYP19A1 | |
| SCHEMBL787256 | 0.75 | ALOX5 (0.59) | ALOX5DRD4AHRKDM4ECYP19A1 | |
| SCHEMBL10109859 | 0.74 | ALOX5 (0.58) | ALOX5DRD4AHRKDM4ECYP19A1 | |
| SCHEMBL17196260 | 0.74 | ALOX5 (0.58) | ALOX5DRD4AHRKDM4ECYP19A1 | |
| SCHEMBL7962346 | 0.74 | ALOX5 (0.54) | ALOX5DRD4AHRKDM4ECYP19A1 | |
| SCHEMBL7035976 | 0.72 | ALDH1A1 (0.43) | ALOX5AHRKDM4ECYP19A1CYP11B1 | |
| SCHEMBL21436953 | 0.71 | ALOX5 (0.51) | ALOX5DRD4AHRKDM4ECYP19A1 | |
| SCHEMBL20982326 | 0.71 | ALOX5 (0.51) | ALOX5DRD4KDM4EMEN1KMT2A | |
| SCHEMBL8374054 | 0.71 | ALOX5 (0.55) | ALOX5DRD4AHRKDM4ECYP19A1 | |
| SCHEMBL19768712 | 0.71 | ALOX5 (0.51) | ALOX5DRD4AHRKDM4ECYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010137018-A1 | PIPERAZINE, PIPERIDINE AND TETRAHYDROPYRIDINE DERIVATIVES AND THEIR PHARMACEUTICAL USE | ATIR HOLDING S.A. (LU) | 2010-12-02 | — | — | WO | disclosed |