SCHEMBL25301757

SCHEMBL25301757

COc1cc2c(C)nn(C(C)C)c2c2ccccc12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PDE1A P54750 3/20 0.44
▸ PDE1B Q01064 3/20 0.44
▸ PDE1C Q14123 3/20 0.44
▸ MPO P05164 3/20 0.44
▸ ATM Q13315 5/20 0.43
▸ MEN1 O00255 5/20 0.43
▸ KMT2A Q03164 5/20 0.43
▸ KDM4E B2RXH2 5/20 0.43
▸ MAPT P10636 4/20 0.43
▸ ALDH1A1 P00352 3/20 0.43
▸ LMNA P02545 1/20 0.43
▸ POLB P06746 1/20 0.43
▸ HPGD P15428 1/20 0.43
▸ L3MBTL1 Q9Y468 1/20 0.41
▸ SMN1; SMN2 Q16637 2/20 0.39
▸ NPSR1 Q6W5P4 1/20 0.38
▸ TDP1 Q9NUW8 1/20 0.38
▸ NPC1 O15118 1/20 0.36
▸ RAB9A P51151 1/20 0.36
▸ RAC1 P63000 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31037076 0.85 MPO (0.44) PDE1APDE1BPDE1CMPOATM
SCHEMBL25302065 0.80 ATM (0.49) ATMMEN1KMT2AKDM4EMAPT
SCHEMBL29405109 0.80 ATM (0.49) ATMMEN1KMT2AKDM4EMAPT
SCHEMBL29404957 0.79 KDM4E (0.42) PDE1APDE1BPDE1CMPOKDM4E
SCHEMBL25256662 0.79 KDM4E (0.42) PDE1APDE1BPDE1CMPOKDM4E
SCHEMBL25257906 0.78 ALDH1A1 (0.56) MPOATMMEN1KMT2AKDM4E
SCHEMBL29404485 0.78 ALDH1A1 (0.56) MPOATMMEN1KMT2AKDM4E
SCHEMBL25254447 0.77 MPO (0.44) PDE1APDE1BPDE1CMPOATM
SCHEMBL29405726 0.77 MPO (0.44) PDE1APDE1BPDE1CMPOATM
SCHEMBL25253315 0.75 LMNA (0.52) ATMMEN1KMT2AKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12570613-B2 Imidazoquinoline or benzoindazolone compound and intermediate for preparing same LMITO THERAPEUTICS INC. (KR) 2026-03-10 — — US disclosed
US-20240034719-A1 IMIDAZOQUINOLINE OR BENZOINDAZOLONE COMPOUND AND INTERMEDIATE FOR PREPARING SAME LMITO THERAPEUTICS INC. (KR) 2024-02-01 — — US disclosed
EP-4212530-A1 IMIDAZOLQUINOLINE OR BENZOINDAZOLONE COMPOUND AND INTERMEDIATE FOR PREPARING SAME Lmito Therapeutics Inc. (KR) 2023-07-19 — — EP disclosed
CN-115956071-A Imidazoquinoline or benzindazolone compounds and intermediates for their preparation LMITO药业株式会社 2023-04-11 — — CN disclosed
WO-2022039460-A1 IMIDAZOLQUINOLINE OR BENZOINDAZOLONE COMPOUND AND INTERMEDIATE FOR PREPARING SAME 주식회사 엘마이토테라퓨틱스 2022-02-24 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240034719-A1 IMIDAZOQUINOLINE OR BENZOINDAZOLONE COMPOUND AND INTERMEDIATE FOR PREPARING SAME NQO1, NFE2L2, KEAP1 PDE1A 2846/4885PDE1B 3600/4885PDE1C 3210/4885
US-12570613-B2 Imidazoquinoline or benzoindazolone compound and intermediate for preparing same NQO1, CBR1, NFE2L2 PDE1A 4033/4885PDE1B 4246/4885PDE1C 4262/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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