Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 4/20 | 0.43 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31037076 | 0.84 | MPO (0.44) | MPOGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL29404957 | 0.81 | KDM4E (0.42) | MPOALDH1A1CYP1A2CYP2C19ESR1 | |
| SCHEMBL25256662 | 0.81 | KDM4E (0.42) | MPOALDH1A1CYP1A2CYP2C19ESR1 | |
| SCHEMBL31037105 | 0.78 | NPC1 (0.44) | MPOEP300GABRA1GABRG2GABRB3 | |
| SCHEMBL31037092 | 0.74 | MPO (0.57) | MPOEP300LMNAHTTPOLB | |
| SCHEMBL31037087 | 0.74 | POLB (0.40) | EP300CYP11B1CYP11B2POLB | |
| SCHEMBL28719142 | 0.71 | CYP11B1 (0.41) | CYP11B1CYP11B2POLBKDM4EMAPT | |
| SCHEMBL31037068 | 0.71 | CYP11B1 (0.41) | CYP11B1CYP11B2POLBKDM4EMAPT | |
| SCHEMBL13925891 | 0.71 | POLB (0.52) | MPOALDH1A1CYP1A2CYP2C19LMNA | |
| SCHEMBL25301757 | 0.70 | PDE1A (0.44) | MPOALDH1A1LMNAPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113454068-B | Benzonazolone compounds and intermediates thereof | LMITO药业株式会社 | 2024-08-02 | — | — | CN | disclosed |