SCHEMBL294053

SCHEMBL294053

COc1cc(Br)cc(C=O)c1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 18/20 1.00
LMNA P02545 1/20 0.55
MAPT P10636 1/20 0.55
IGF1R P08069 1/20 0.54
TLR2 O60603 1/20 0.53
TLR1 Q15399 1/20 0.53
TLR6 Q9Y2C9 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30159258 1.00 ERN1 (1.00) ERN1LMNAMAPTIGF1RTLR2
SCHEMBL15331811 0.83 ERN1 (0.71) ERN1LMNAMAPTIGF1R
SCHEMBL15331813 0.83 ERN1 (0.71) ERN1LMNAMAPTIGF1R
SCHEMBL16475647 0.81 ERN1 (0.68) ERN1LMNAMAPTIGF1RTLR2
SCHEMBL11052763 0.81 ERN1 (0.70) ERN1LMNAMAPTTLR2TLR1
SCHEMBL1620544 0.81 ERN1 (0.68) ERN1LMNAMAPTIGF1R
SCHEMBL544809 0.80 ERN1 (0.78) ERN1
SCHEMBL1879373 0.80 ERN1 (0.64) ERN1LMNAMAPT
SCHEMBL8679776 0.79 ERN1 (0.68) ERN1LMNAMAPTTLR2TLR1
SCHEMBL881403 0.79 ERN1 (1.00) ERN1LMNAMAPTTLR2TLR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 385 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113563163-A Synthetic method of 5-bromo-1, 2, 3-trimethoxybenzene 南京伊派森化学科技有限公司 2021-10-29 CN claimed
CN-108440577-B Mixed copper-based complex and preparation method and application thereof 桂林医学院 2020-05-12 CN claimed
CN-105601561-B Piperidones Schiff base derivatives of 3,5 2 aryl methylene 4 with antitumor activity and preparation method thereof 滨州医学院 2018-04-10 CN claimed
CN-105601561-A 3,5-diaryl methylene-4-piperidone Schiff base derivatives with antitumor activity and preparing method thereof BINZHOU MEDICAL COLLEGE 2016-05-25 CN claimed
CN-104130160-A Acylhydrazone compound containing aromatic ring and preparation method thereof UNIV XI AN SCI & TECHNOLOGY 2014-11-05 CN claimed
US-20060084176-A1 Detection of uronium salts YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2006-04-20 US claimed
US-6797745-B1 Hot melt inks containing styrene or terpene polymers XEROX CORPORATION 2004-09-28 US claimed
US-6780900-B1 ALDEHYDE COPOLYMER INK VEHICLE, A NONPOLYMERIC ALDEHYDE VISCOSITY MODIFIER, COLORANT, AN OPTIONAL CONDUCTIVITY ENHANCING AGENT, AN OPTIONAL ANTIOXIDANT, AND AN OPTIONAL UV ABSORBER XEROX CORPORATION 2004-08-24 US claimed
US-12558341-B2 Oral complement factor D inhibitors BIOCRYST PHARMACEUTICALS, INC. (US) 2026-02-24 US disclosed
US-12503477-B2 Colony stimulating factor-1 receptor (CSF-1R) inhibitors GENZYME CORPORATION 2025-12-23 US disclosed
US-20250231180-A1 FLUORESCENT TURN-ON CHEMOSENSORS FOR DETECTION OF ALUMINUM ION AND AZIDE MORGAN STATE UNIVERSITY 2025-07-17 US disclosed
US-20250231180-A1 FLUORESCENT TURN-ON CHEMOSENSORS FOR DETECTION OF ALUMINUM ION AND AZIDE MORGAN STATE UNIVERSITY 2025-07-17 US disclosed
WO-2025124544-A1 3,4-DIHYDRO-2H-BENZO[B][1,4]DIOXEPANE COMPOUND, AND PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF 华润医药研究院(深圳)有限公司 2025-06-19 WO disclosed
US-20250186391-A1 ORAL COMPLEMENT FACTOR D INHIBITORS WILMINGTON TRUST, NATIONAL ASSOCIATION 2025-06-12 US disclosed
US-5620991-A ANTICOAGULANTS DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1997-04-15 US disclosed
WO-1996040108-A1 MULTIDENTATE METAL COMPLEXES AND METHODS OF MAKING AND USING THEREOF WASHINGTON UNIVERSITY (US) 1996-12-19 WO disclosed
US-5576343-A ANTICOAGULANTS; BLOOD-COAGULATION FACTOR X INHIBITORS DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1996-11-19 US disclosed
EP-0540051-B1 Aromatic amidine derivatives and salts thereof DAIICHI SEIYAKU CO (JP) 1996-04-03 EP disclosed
EP-0540051-A1 Aromatic amidine derivatives and salts thereof DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1993-05-05 EP disclosed
EP-0103173-A1 Carbamic-acid esters, process and starting material for their preparation, parasiticides containing these esters as active products, as well as the use of such esters and agents in combating parasites F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1984-03-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12558341-B2 Oral complement factor D inhibitors CFD, CFH, CFB ERN1 3303/4885LMNA 1698/4885MAPT 4793/4885
US-20250231180-A1 FLUORESCENT TURN-ON CHEMOSENSORS FOR DETECTION OF ALUMINUM ION AND AZIDE MYBBP1A, MYB, NCS1 ERN1 2902/4885LMNA 274/4885MAPT 3684/4885
US-12503477-B2 Colony stimulating factor-1 receptor (CSF-1R) inhibitors CSF1R, CSF3R, IL1RN ERN1 2603/4885LMNA 4848/4885MAPT 1811/4885
US-20250186391-A1 ORAL COMPLEMENT FACTOR D INHIBITORS CFD, CFH, CFB ERN1 1832/4885LMNA 1844/4885MAPT 3561/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.