SCHEMBL29405642

SCHEMBL29405642

N=c1ccn(-c2ncccn2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.40
POLB P06746 1/20 0.40
INMT O95050 2/20 0.39
RPS6KA5 O75582 1/20 0.36
MAPK1 P28482 1/20 0.34
MAPT P10636 3/20 0.33
TUBB4A P04350 1/20 0.33
TUBB P07437 1/20 0.33
TUBA3C P0DPH7 1/20 0.33
TUBA1B P68363 1/20 0.33
TUBA4A P68366 1/20 0.33
TUBB4B P68371 1/20 0.33
TUBB3 Q13509 1/20 0.33
TUBB2A Q13885 1/20 0.33
TUBB8 Q3ZCM7 1/20 0.33
TUBA3E Q6PEY2 1/20 0.33
TUBA1A Q71U36 1/20 0.33
TUBA1C Q9BQE3 1/20 0.33
TUBB6 Q9BUF5 1/20 0.33
TUBB2B Q9BVA1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3262365 0.76 MAPK1 (0.44) LMNAPOLBRPS6KA5MAPK1MAPT
SCHEMBL6325483 0.74 ALDH1A1 (0.33) LMNAMAPTALDH1A1KMT2AMEN1
SCHEMBL11994523 0.64 TUBB4A (0.38) POLBRPS6KA5MAPTTUBB4ATUBB
SCHEMBL31659438 0.64 MAPT (0.35) LMNAPOLBRPS6KA5MAPTALDH1A1
SCHEMBL989991 0.63 CYP3A4 (0.52) LMNAMAPK1MAPTALDH1A1KMT2A
SCHEMBL17104866 0.58 ALDH1A1 (0.34) LMNAPOLBRPS6KA5MAPTALDH1A1
SCHEMBL9848539 0.58 ALDH1A1 (0.51) LMNAPOLBMAPK1MAPTALDH1A1
SCHEMBL7593026 0.58 ALDH1A1 (0.60) LMNAPOLBRPS6KA5MAPK1MAPT
SCHEMBL2472665 0.58
SCHEMBL2146662 0.57 MAPT (0.42) POLBMAPK1MAPTALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114463458-A Local low-rank nuclear magnetic resonance image-based motion artifact correction method and device 山东颐邦齐鲁医生集团管理有限公司 2022-05-10 CN claimed
CN-114095229-A Method, device and system for constructing data transmission protocol of energy Internet 中国电力科学研究院有限公司 2022-02-25 CN claimed
CN-122012499-A Promoter library suitable for bifidobacterium breve and application 江南大学 2026-05-12 CN disclosed
WO-2025262138-A2 THERMOPHILIC BACTERIUM COMPRISING A SURFACE-DISPLAYED CARBONIC ANHYDRASE DANMARKS TEKNISKE UNIVERSITET (DK) 2025-12-26 WO disclosed
US-20250321125-A1 MAGNETIC POLE POSITION DETERMINING SYSTEM AND METHOD Qingdao Hisense Hitachi Air-conditioning Systems Co., Ltd. (CN) 2025-10-16 US disclosed
US-20250276060-A1 SELECTIVELY ALTERING MICROBIOTA FOR IMMUNE MODULATION SNIPR TECHNOLOGIES LIMITED (GB) 2025-09-04 US disclosed
EP-4570253-A2 ALTERING MICROBIAL POPULATIONS & MODIFYING MICROBIOTA SNIPR Technologies Limited (GB) 2025-06-18 EP disclosed
CN-119899756-A Construction method and application of recombinant yarrowia lipolytica capable of producing succinic acid in high yield 南京工业大学 2025-04-29 CN disclosed
WO-2024179271-A1 SYSTEM FOR DETERMINING POSITION OF MAGNETIC POLE 青岛海信日立空调系统有限公司 2024-09-06 WO disclosed
EP-4334468-A2 COMPOSITIONS COMPRISING NULLOMERS AND METHODS OF USING THE SAME FOR CANCER DETECTION AND DIAGNOSIS The Regents of The University of California (US) 2024-03-13 EP disclosed
EP-4233546-A2 ALTERING MICROBIAL POPULATIONS & MODIFYING MICROBIOTA SNIPR Technologies Limited (GB) 2023-08-30 EP disclosed
EP-4169383-A1 ALTERING MICROBIAL POPULATIONS & MODIFYING MICROBIOTA SNIPR Technologies Limited (GB) 2023-04-26 EP disclosed
US-11471530-B2 Selectively altering microbiota for immune modulation SNIPR TECHNOLOGIES LIMITED (GB) 2022-10-18 US disclosed
US-20220273696-A1 ALTERING MICROBIAL POPULATIONS & MODIFYING MICROBIOTA SNIPR TECHNOLOGIES LIMITED (GB) 2022-09-01 US disclosed
EP-4005386-A1 ALTERING MICROBIAL POPULATIONS & MODIFYING MICROBIOTA SNIPR Technologies Limited (GB) 2022-06-01 EP disclosed
CN-114463458-A Local low-rank nuclear magnetic resonance image-based motion artifact correction method and device 山东颐邦齐鲁医生集团管理有限公司 2022-05-10 CN disclosed
CN-114095229-A Method, device and system for constructing data transmission protocol of energy Internet 中国电力科学研究院有限公司 2022-02-25 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220273696-A1 ALTERING MICROBIAL POPULATIONS & MODIFYING MICROBIOTA MGAM, COMT, CEL LMNA 4643/4885POLB 360/4885INMT 83/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.