SCHEMBL29405769

SCHEMBL29405769

N[C@@H](Cc1c[nH]c2cc(Cl)ccc12)C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 3/20 0.66
▸ KDM4E B2RXH2 2/20 0.66
▸ LMNA P02545 2/20 0.66
▸ MAPT P10636 2/20 0.66
▸ TSHR P16473 2/20 0.66
▸ BLM P54132 2/20 0.66
▸ PMP22 Q01453 2/20 0.66
▸ MEN1 O00255 2/20 0.66
▸ MPO P05164 1/20 0.66
▸ HIF1A Q16665 1/20 0.66
▸ PTPRA P18433 1/20 0.65
▸ CYP2C19 P33261 1/20 0.62
▸ HTR2A P28223 3/20 0.61
▸ ALDH1A1 P00352 1/20 0.61
▸ CYP3A4 P08684 1/20 0.61
▸ HTR1A P08908 1/20 0.61
▸ ADORA3 P0DMS8 1/20 0.61
▸ ALOX15 P16050 1/20 0.61
▸ NFKB1 P19838 1/20 0.61
▸ HTR2C P28335 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL128685 1.00 KMT2A (0.66) KMT2AKDM4ELMNAMAPTTSHR
SCHEMBL30381542 1.00 KMT2A (0.66) KMT2AKDM4ELMNAMAPTTSHR
SCHEMBL456668 1.00 KMT2A (0.66) KMT2AKDM4ELMNAMAPTTSHR
SCHEMBL623336 1.00 KMT2A (0.66) KMT2AKDM4ELMNAMAPTTSHR
SCHEMBL18029175 1.00 KMT2A (0.66) KMT2AKDM4ELMNAMAPTTSHR
SCHEMBL11604913 0.93 PTPRA (0.58) KMT2AKDM4ELMNAMAPTTSHR
SCHEMBL11602575 0.93 PTPRA (0.58) KMT2AKDM4ELMNAMAPTTSHR
SCHEMBL11602580 0.93 PTPRA (0.58) KMT2AKDM4ELMNAMAPTTSHR
SCHEMBL195273 0.89 HTR2A (0.73) KMT2AKDM4ELMNAMAPTTSHR
SCHEMBL21309683 0.89 HTR2A (0.73) KMT2AKDM4ELMNAMAPTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122094701-A TLR3 binding bicyclic peptide ligands — 2026-05-26 — — CN claimed
WO-2025046244-A1 TLR3 BINDING BICYCLIC PEPTIDE LIGANDS BICYCLETX LIMITED (GB) 2025-03-06 — — WO claimed
EP-4274838-B1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR NK CELLS BICYCLETX LTD (GB) 2024-09-25 — — EP claimed
US-11904020-B2 Bicyclic peptide ligands specific for TREM2 BICYCLETX LIMITED (GB) 2024-02-20 — — US claimed
CN-117529489-A Bicyclic peptide ligands specific for NK cells 拜斯科技术开发有限公司 2024-02-06 — — CN claimed
CN-117337295-A Bicyclic peptide ligands specific for TREM2 拜斯科技术开发有限公司 2024-01-02 — — CN claimed
EP-4274838-A2 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR NK CELLS BicycleTx Limited (GB) 2023-11-15 — — EP claimed
US-20220296726-A1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR TREM2 BICYCLETX LIMITED (GB) 2022-09-22 — — US claimed
WO-2022148974-A2 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR NK CELLS BICYCLETX LIMITED (GB) 2022-07-14 — — WO claimed
EP-4021476-A1 SYNTHETIC ANTIMICROBIAL PEPTIDES AJK Biopharmaceutical, LLC (US) 2022-07-06 — — EP claimed
CN-122094701-A TLR3 binding bicyclic peptide ligands — 2026-05-26 — — CN disclosed
US-20260102461-A1 PROTEIN SCAFFOLDS FOR DISORDERED REGIONS AIKIUM INC (US) 2026-04-16 — — US disclosed
US-20260071243-A1 BIOLOGICAL PRODUCTION OF TRYPTOPHAN-DERIVED PRODUCTS UNIV TEXAS (US) 2026-03-12 — — US disclosed
US-20250387450-A1 PROTEIN SCAFFOLDS FOR DISORDERED REGIONS AIKIUM INC (US) 2025-12-25 — — US disclosed
WO-2025245483-A1 METHODS AND COMPOSITIONS FLAGSHIP PIONEERING INNOVATIONS VII, LLC (US) 2025-11-27 — — WO disclosed
WO-2022081721-A1 NANOMATERIAL AND METHODS OF USE THEREOF UNIVERSITY OF CONNECTICUT (US) 2022-04-21 — — WO disclosed
EP-3983543-A1 REAGENTS AND METHODS FOR REPLICATION, TRANSCRIPTION, AND TRANSLATION IN SEMI-SYNTHETIC ORGANISMS The Scripps Research Institute (US) 2022-04-20 — — EP disclosed
EP-3966201-A1 THIOSEMICARBAZATES AND USES THEREOF The Feinstein Institutes for Medical Research (US) 2022-03-16 — — EP disclosed
EP-3966223-A1 PEPTIDOMIMETIC AGENTS, SYNTHESIS AND USES THEREOF The Feinstein Institutes for Medical Research (US) 2022-03-16 — — EP disclosed
WO-2022047579-A1 HALOGENATED PSILOCYBIN DERIVATIVES AND METHODS OF USING MAGICMED INDUSTRIES INC. (CA) 2022-03-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11904020-B2 Bicyclic peptide ligands specific for TREM2 APP, TIMCC, ADM2 KMT2A 3481/4885KDM4E 4811/4885LMNA 1950/4885
US-20220296726-A1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR TREM2 APP, TIMCC, ADM2 KMT2A 3481/4885KDM4E 4811/4885LMNA 1950/4885
US-20250387450-A1 PROTEIN SCAFFOLDS FOR DISORDERED REGIONS SPPL2B, SPPL2A, CRYZ KMT2A 4735/4885KDM4E 4295/4885LMNA 1703/4885
US-20260102461-A1 PROTEIN SCAFFOLDS FOR DISORDERED REGIONS MAX, CRYZ, STAMBP KMT2A 4620/4885KDM4E 4268/4885LMNA 948/4885
US-20260071243-A1 BIOLOGICAL PRODUCTION OF TRYPTOPHAN-DERIVED PRODUCTS TPH1, TPH2, SLC6A4 KMT2A 1283/4885KDM4E 3485/4885LMNA 4867/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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