Sugi Predict

Sugi Predict / Compounds / SCHEMBL128685

SCHEMBL128685

SCHEMBL128685

N[C@H](Cc1c[nH]c2cc(Cl)ccc12)C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 3/20 0.66
▸ KDM4E B2RXH2 2/20 0.66
▸ LMNA P02545 2/20 0.66
▸ MAPT P10636 2/20 0.66
▸ TSHR P16473 2/20 0.66
▸ BLM P54132 2/20 0.66
▸ PMP22 Q01453 2/20 0.66
▸ MEN1 O00255 2/20 0.66
▸ MPO P05164 1/20 0.66
▸ HIF1A Q16665 1/20 0.66
▸ PTPRA P18433 1/20 0.65
▸ CYP2C19 P33261 1/20 0.62
▸ HTR2A P28223 3/20 0.61
▸ ALDH1A1 P00352 1/20 0.61
▸ CYP3A4 P08684 1/20 0.61
▸ HTR1A P08908 1/20 0.61
▸ ADORA3 P0DMS8 1/20 0.61
▸ ALOX15 P16050 1/20 0.61
▸ NFKB1 P19838 1/20 0.61
▸ HTR2C P28335 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18029175 1.00 KMT2A (0.66) KMT2AKDM4ELMNAMAPTTSHR
SCHEMBL623336 1.00 KMT2A (0.66) KMT2AKDM4ELMNAMAPTTSHR
SCHEMBL29405769 1.00 KMT2A (0.66) KMT2AKDM4ELMNAMAPTTSHR
SCHEMBL30381542 1.00 KMT2A (0.66) KMT2AKDM4ELMNAMAPTTSHR
SCHEMBL456668 1.00 KMT2A (0.66) KMT2AKDM4ELMNAMAPTTSHR
SCHEMBL11602575 0.93 PTPRA (0.58) KMT2AKDM4ELMNAMAPTTSHR
SCHEMBL11604913 0.93 PTPRA (0.58) KMT2AKDM4ELMNAMAPTTSHR
SCHEMBL11602580 0.93 PTPRA (0.58) KMT2AKDM4ELMNAMAPTTSHR
SCHEMBL31642414 0.89 HTR2A (0.73) KMT2AKDM4ELMNAMAPTTSHR
SCHEMBL21309683 0.89 HTR2A (0.73) KMT2AKDM4ELMNAMAPTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 655 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240188613-A1 SWEETENER COMPOSITIONS COMPRISING MOGROSIDES AND USES THEREOF FIRMENICH INCORPORATED 2024-06-13 — — US claimed
US-20240090547-A1 SWEETENER COMPOSITIONS COMPRISING MOGROSIDES AND USES THEREOF FIRMENICH INCORPORATED 2024-03-21 — — US claimed
US-20240065302-A1 SWEETENER COMPOSITIONS COMPRISING MOGROSIDES AND USES THEREOF FIRMENICH INCORPORATED 2024-02-29 — — US claimed
CN-116963609-A Sweetener composition comprising mogrosides and uses thereof 弗门尼舍公司 2023-10-27 — — CN claimed
EP-4258895-A1 SWEETENER COMPOSTIONS COMPRISING SIAMENOSIDE I AND USES THEREOF Firmenich Incorporated (US) 2023-10-18 — — EP claimed
EP-4258897-A1 SWEETENER COMPOSITIONS COMPRISING MOGROSIDES AND USES THEREOF Firmenich Incorporated (US) 2023-10-18 — — EP claimed
EP-4258896-A1 SWEETENER COMPOSITIONS COMPRISING MOGROSIDES AND USES THEREOF Firmenich Incorporated (US) 2023-10-18 — — EP claimed
WO-2022155669-A1 SWEETENER COMPOSITIONS COMPRISING MOGROSIDES AND USES THEREOF FIRMENICH INCORPORATED (US) 2022-07-21 — — WO claimed
WO-2022155668-A1 SWEETENER COMPOSTIONS COMPRISING SIAMENOSIDE I AND USES THEREOF FIRMENICH INCORPORATED (US) 2022-07-21 — — WO claimed
WO-2022155667-A1 SWEETENER COMPOSITIONS COMPRISING MOGROSIDES AND USES THEREOF FIRMENICH INCORPORATED (US) 2022-07-21 — — WO claimed
CN-108315370-A A kind of preparation method of halogen tryptophan 滨海吉尔多肽有限公司 2018-07-24 — — CN claimed
US-20180086751-A1 SWEETENER COMPOSITION SENOMYX, INC. 2018-03-29 — — US claimed
US-20170354175-A1 SWEETENER COMPOSITION SENOMYX, INC. 2017-12-14 — — US claimed
US-20170105432-A1 SWEETENER AND FLAVOR ENHANCER FORMULATIONS SENOMYX, INC. 2017-04-20 — — US claimed
US-20110045547-A1 ISOMERASES AND EPIMERASES AND METHODS OF USING DE SOUZA MERVYN L 2011-02-24 — — US claimed
CN-101970679-A Aminotransferase and oxidoreductase nucleic acids and polypeptides and methods of use CARGILL INC 2011-02-09 — — CN claimed
WO-2011002469-A1 ISOMERASES AND EPIMERASES AND METHODS OF USING CARGILL, INCORPORATED (US) 2011-01-06 — — WO claimed
EP-2225390-A1 AMINOTRANSFERASE AND OXIDOREDUCTASE NUCLEIC ACIDS AND POLYPEPTIDES AND METHODS OF USING Cargill, Incorporated (US) 2010-09-08 — — EP claimed
WO-2009088482-A1 AMINOTRANSFERASE AND OXIDOREDUCTASE NUCLEIC ACIDS AND POLYPEPTIDES AND METHODS OF USING CARGILL, INCORPORATED (US) 2009-07-16 — — WO claimed
WO-2009088442-A2 ISOMERASES AND EPIMERASES AND METHODS OF USING CARGILL, INCORPORATED (US) 2009-07-16 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180086751-A1 SWEETENER COMPOSITION TAS2R50, TAS1R2, TAS2R10 KMT2A 605/4885KDM4E 2019/4885LMNA 4573/4885
US-20170105432-A1 SWEETENER AND FLAVOR ENHANCER FORMULATIONS TAS2R50, TAS2R10, TAS2R40 KMT2A 600/4885KDM4E 980/4885LMNA 4527/4885
US-20170354175-A1 SWEETENER COMPOSITION TAS1R2, TAS1R1, TAS2R50 KMT2A 763/4885KDM4E 2566/4885LMNA 4642/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.