Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 7/20 | 0.36 |
| ▸ | APP | P05067 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.30 |
| ▸ | PTGES | O14684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29725739 | 1.00 | ALOX5 (0.36) | ALOX5APPPTPN1NR1H4BACE1 | |
| SCHEMBL30067164 | 0.98 | ALOX5 (0.36) | ALOX5APPPTPN1NR1H4BACE1 | |
| SCHEMBL29725684 | 0.98 | ALOX5 (0.36) | ALOX5APPPTPN1NR1H4BACE1 | |
| SCHEMBL30678552 | 0.98 | ALOX5 (0.36) | ALOX5APPPTPN1NR1H4BACE1 | |
| SCHEMBL29381348 | 0.98 | ALOX5 (0.36) | ALOX5APPPTPN1NR1H4BACE1 | |
| SCHEMBL24632196 | 0.98 | ALOX5 (0.36) | ALOX5APPPTPN1NR1H4BACE1 | |
| SCHEMBL31114965 | 0.98 | ALOX5 (0.36) | ALOX5APPPTPN1NR1H4BACE1 | |
| SCHEMBL2624852 | 0.98 | ALOX5 (0.36) | ALOX5APPPTPN1NR1H4BACE1 | |
| SCHEMBL30673511 | 0.98 | ALOX5 (0.36) | ALOX5APPPTPN1NR1H4BACE1 | |
| SCHEMBL29330492 | 0.98 | ALOX5 (0.36) | ALOX5APPPTPN1NR1H4BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240189280-A1 | DRUG FOR TREATING OR PREVENTING CEREBRAL HEMORRHAGE, AND METHOD FOR TREATING OR PREVENTING CEREBRAL HEMORRHAGE USING THE DRUG | CORXEL PHARMACEUTICALS HONG KONG LIMITED (CN) | 2024-06-13 | — | — | US | claimed |
| EP-4252752-A1 | DRUG FOR TREATMENT OR PREVENTION OF CEREBRAL HEMORRHAGE, AND METHOD FOR TREATMENT OR PREVENTION OF CEREBRAL HEMORRHAGE USING SAID DRUG | Biogen MA Inc. (US) | 2023-10-04 | — | — | EP | claimed |
| CN-116761600-A | Medicament for treating or preventing cerebral hemorrhage and method for treating or preventing cerebral hemorrhage using the same | 渤健马萨诸塞州股份有限公司 | 2023-09-15 | — | — | CN | claimed |
| US-20220218664-A1 | DRUG AND METHOD FOR TREATING OR PREVENTING COMPLICATIONS FROM DIABETES, USING SAID DRUG | SHOWA UNIVERSITY (JP) | 2022-07-14 | — | — | US | claimed |
| CN-114126711-A | Medicament and method for treating or preventing diabetic complications using the same | 学校法人昭和大学 | 2022-03-01 | — | — | CN | claimed |
| US-12453718-B2 | Drug for treating or preventing cerebral hemorrhage, and method for treating or preventing cerebral hemorrhage using the drug | CORXEL PHARMACEUTICALS HONG KONG LIMITED (CN) | 2025-10-28 | — | — | US | disclosed |
| US-20250099427-A1 | Drug and Method of Treating or Preventing Renal Disease Using Drug | SHOWA MEDICAL UNIVERSITY (JP) | 2025-03-27 | — | — | US | disclosed |
| US-12138244-B2 | Drug and method of treating or preventing renal disease using drug | SHOWA UNIVERSITY (JP) | 2024-11-12 | — | — | US | disclosed |
| US-20240189280-A1 | DRUG FOR TREATING OR PREVENTING CEREBRAL HEMORRHAGE, AND METHOD FOR TREATING OR PREVENTING CEREBRAL HEMORRHAGE USING THE DRUG | CORXEL PHARMACEUTICALS HONG KONG LIMITED (CN) | 2024-06-13 | — | — | US | disclosed |
| US-11850232-B2 | Drug for treating or preventing cerebral hemorrhage, and method for treating or preventing cerebral hemorrhage using the drug | BIOGEN MA INC. (US) | 2023-12-26 | — | — | US | disclosed |
| CN-111936134-B | Pharmaceutical agent and method for treating or preventing kidney disease using the same | 学校法人昭和大学 | 2023-12-08 | — | — | CN | disclosed |
| EP-4252752-A1 | DRUG FOR TREATMENT OR PREVENTION OF CEREBRAL HEMORRHAGE, AND METHOD FOR TREATMENT OR PREVENTION OF CEREBRAL HEMORRHAGE USING SAID DRUG | Biogen MA Inc. (US) | 2023-10-04 | — | — | EP | disclosed |
| CN-116761600-A | Medicament for treating or preventing cerebral hemorrhage and method for treating or preventing cerebral hemorrhage using the same | 渤健马萨诸塞州股份有限公司 | 2023-09-15 | — | — | CN | disclosed |
| US-RE49351-E1 | Cytoprotective agent | BIOGEN MA INC. (US) | 2023-01-03 | — | — | US | disclosed |
| US-20220218664-A1 | DRUG AND METHOD FOR TREATING OR PREVENTING COMPLICATIONS FROM DIABETES, USING SAID DRUG | SHOWA UNIVERSITY (JP) | 2022-07-14 | — | — | US | disclosed |
| CN-114126711-A | Medicament and method for treating or preventing diabetic complications using the same | 学校法人昭和大学 | 2022-03-01 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250099427-A1 | Drug and Method of Treating or Preventing Renal Disease Using Drug | REN, ATP6V1B1, SLC10A1 | ALOX5 117/4885APP 2305/4885PTPN1 3029/4885 |
| US-12138244-B2 | Drug and method of treating or preventing renal disease using drug | REN, ATP6V1B1, SLC10A1 | ALOX5 117/4885APP 2305/4885PTPN1 3029/4885 |
| US-12453718-B2 | Drug for treating or preventing cerebral hemorrhage, and method for treating or preventing cerebral hemorrhage using the drug | PROC, FABP7, SERPINC1 | ALOX5 285/4885APP 592/4885PTPN1 4588/4885 |
| US-20220218664-A1 | DRUG AND METHOD FOR TREATING OR PREVENTING COMPLICATIONS FROM DIABETES, USING SAID DRUG | SLC5A2, SLC5A1, IAPP | ALOX5 71/4885APP 728/4885PTPN1 2665/4885 |
| US-20240189280-A1 | DRUG FOR TREATING OR PREVENTING CEREBRAL HEMORRHAGE, AND METHOD FOR TREATING OR PREVENTING CEREBRAL HEMORRHAGE USING THE DRUG | PROC, FABP7, SERPINC1 | ALOX5 285/4885APP 592/4885PTPN1 4588/4885 |
| US-11850232-B2 | Drug for treating or preventing cerebral hemorrhage, and method for treating or preventing cerebral hemorrhage using the drug | PROC, FABP7, SERPINC1 | ALOX5 285/4885APP 592/4885PTPN1 4588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.