SCHEMBL29407366

SCHEMBL29407366

O=C1C=C(O)C(=O)c2cc(O)ccc21

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 9/20 0.61
ESR1 P03372 8/20 0.61
MAOA P21397 1/20 0.61
UGT1A1 P22309 1/20 0.61
MAOB P27338 1/20 0.61
TTR P02766 1/20 0.46
PTPRC P08575 1/20 0.46
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA7 P43166 1/20 0.44
CA9 Q16790 1/20 0.44
P4HB P07237 1/20 0.44
BACE1 P56817 1/20 0.42
USP7 Q93009 1/20 0.41
USP47 Q96K76 1/20 0.41
ALDH1A1 P00352 2/20 0.41
MAPT P10636 2/20 0.41
KDM4E B2RXH2 1/20 0.41
CYP3A4 P08684 1/20 0.41
HPGD P15428 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5817037 1.00 ESR2 (0.61) ESR2ESR1MAOAUGT1A1MAOB
SCHEMBL5811756 0.92 ESR2 (0.61) ESR2ESR1MAOAUGT1A1MAOB
SCHEMBL30004162 0.92 ESR2 (0.61) ESR2ESR1MAOAUGT1A1MAOB
SCHEMBL18992188 0.84 BCL2 (0.58) ESR2ESR1MAOAUGT1A1MAOB
SCHEMBL8663184 0.81 ESR2 (0.44) ESR2ESR1MAOAUGT1A1MAOB
SCHEMBL10086888 0.80 CA9 (0.44) ESR2ESR1MAOAUGT1A1MAOB
SCHEMBL21013875 0.80 TGM2 (0.39) ESR2ESR1MAOAUGT1A1MAOB
SCHEMBL30490 0.80 S100A4 (0.57) ESR2ESR1MAOAUGT1A1MAOB
SCHEMBL12822632 0.80 ESR2 (0.57) ESR2ESR1MAOAUGT1A1MAOB
SCHEMBL29404998 0.80 MAOA (0.53) ESR2ESR1MAOAUGT1A1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117813710-A Aqueous electrolyte, salt used therein, and redox flow battery using same 三菱化学株式会社 2024-04-02 CN disclosed
CN-107847466-B Formulations and methods for modulating wound healing 贝欧曼蒂克丝公司 2024-02-06 CN disclosed
CN-114195814-B Hydroxy naphthalenone-phenylboronic acid compound, preparation method and application 中国药科大学 2023-07-21 CN disclosed
CN-114195814-A Hydroxy naphthalenone-phenylboronic acid compound, preparation method and application 中国药科大学 2022-03-18 CN disclosed