Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAG1 | P54619 | 2/20 | 0.56 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.56 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.56 |
| ▸ | ALPL | P05186 | 3/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.50 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.50 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.50 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29408161 | 0.81 | PRKAG1 (0.54) | PRKAG1PRKAA1PRKAB1ALPLCA9 | |
| SCHEMBL9057955 | 0.81 | KDM4E (0.47) | SMN1; SMN2MAPTDYRK1BALDH1A1HPGD | |
| SCHEMBL4765285 | 0.75 | SMN1; SMN2 (0.56) | PRKAG1PRKAA1PRKAB1ALPLCA9 | |
| SCHEMBL22678560 | 0.72 | CDK2 (0.46) | SMN1; SMN2MAPTDYRK1BALDH1A1HPGD | |
| SCHEMBL7441041 | 0.71 | LMNA (0.57) | PRKAG1PRKAA1PRKAB1ALPLCA9 | |
| SCHEMBL10642212 | 0.71 | LMNA (0.44) | PRKAG1PRKAA1PRKAB1PRKAB2PRKAA2 | |
| SCHEMBL9353501 | 0.71 | PRKAG1 (0.53) | PRKAG1PRKAA1PRKAB1ALPLCA9 | |
| SCHEMBL8075999 | 0.70 | SMN1; SMN2 (0.49) | PRKAG1PRKAA1PRKAB1ALPLCA9 | |
| SCHEMBL3546318 | 0.70 | KMT2A (0.59) | PRKAG1PRKAA1PRKAB1ALPLCA9 | |
| SCHEMBL8890557 | 0.69 | SMN1; SMN2 (0.53) | ALPLCA9SMN1; SMN2HTTMAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114127049-A | ACSS2 inhibitors and methods of use thereof | 美特波米德有限公司 | 2022-03-01 | — | — | CN | disclosed |