Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.68 |
| ▸ | PKM | P14618 | 1/20 | 0.68 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.67 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.67 |
| ▸ | AKR1B1 | P15121 | 7/20 | 0.66 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.66 |
| ▸ | MMP3 | P08254 | 2/20 | 0.66 |
| ▸ | MMP13 | P45452 | 2/20 | 0.66 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19736167 | 1.00 | MEN1 (0.68) | MEN1KMT2APSMD14PKMPTPN12 | |
| SCHEMBL29408612 | 0.91 | PKM (0.78) | MEN1KMT2APSMD14PKMPTPN12 | |
| SCHEMBL19736229 | 0.91 | PKM (0.78) | MEN1KMT2APSMD14PKMPTPN12 | |
| SCHEMBL29408613 | 0.90 | MEN1 (0.68) | MEN1KMT2APSMD14PKMPTPN12 | |
| SCHEMBL19736164 | 0.90 | MEN1 (0.68) | MEN1KMT2APSMD14PKMPTPN12 | |
| SCHEMBL25992865 | 0.90 | MEN1 (0.68) | MEN1KMT2APSMD14PKMPTPN12 | |
| SCHEMBL14426474 | 0.88 | PTPN12 (0.77) | MEN1KMT2APTPN12PTPN22AKR1B1 | |
| SCHEMBL6720211 | 0.84 | MEN1 (0.71) | MEN1KMT2AAKR1B1PTPN1POLB | |
| SCHEMBL25196230 | 0.82 | PTPN12 (0.69) | MEN1KMT2APTPN12PTPN22AKR1B1 | |
| SCHEMBL29408614 | 0.82 | MEN1 (0.66) | MEN1KMT2APSMD14PKMPTPN12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220378751-A1 | INHIBITING DIHYDROFOLATE REDUCTASE IN A MICROORGANISM | VERSITECH LIMITED (HK) | 2022-12-01 | — | — | US | disclosed |
| CN-109414432-B | Antimicrobial compounds and methods of use thereof | 港大科桥有限公司 | 2022-03-08 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220378751-A1 | INHIBITING DIHYDROFOLATE REDUCTASE IN A MICROORGANISM | DHFR, BLVRB, QDPR | MEN1 3181/4885KMT2A 1948/4885PSMD14 3177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.