Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.62 |
| ▸ | NPC1 | O15118 | 5/20 | 0.62 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.59 |
| ▸ | KDM4A | O75164 | 2/20 | 0.57 |
| ▸ | KDM5C | P41229 | 2/20 | 0.57 |
| ▸ | KDM4B | O94953 | 1/20 | 0.57 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | JAK2 | O60674 | 1/20 | 0.57 |
| ▸ | TYK2 | P29597 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | KDM6B | O15054 | 1/20 | 0.54 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.54 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.54 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.52 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1569099 | 1.00 | RAB9A (0.62) | RAB9ANPC1HCAR3KDM4AKDM5C | |
| SCHEMBL1767522 | 0.89 | RAB9A (0.61) | RAB9ANPC1HCAR3ATMJAK2 | |
| SCHEMBL7669653 | 0.85 | RAB9A (0.64) | RAB9ANPC1HCAR3ATMJAK2 | |
| SCHEMBL21867435 | 0.84 | RAB9A (0.60) | RAB9ANPC1KDM5CKDM5BATM | |
| SCHEMBL20521961 | 0.82 | SMN1; SMN2 (0.55) | RAB9ANPC1KDM5BATMKMT2A | |
| SCHEMBL24349065 | 0.82 | RAB9A (0.61) | RAB9ANPC1HCAR3ATMJAK2 | |
| SCHEMBL17065565 | 0.82 | NPC1 (0.89) | RAB9ANPC1ATMKMT2AMEN1 | |
| SCHEMBL30362420 | 0.82 | NPC1 (0.61) | RAB9ANPC1ATMJAK2TYK2 | |
| SCHEMBL29899082 | 0.82 | NPC1 (0.61) | RAB9ANPC1HCAR3ATMJAK2 | |
| SCHEMBL28650577 | 0.82 | JAK2 (0.63) | RAB9ANPC1ATMJAK2TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220202792-A1 | METHODS AND COMPOSITIONS FOR TREATING CHRONIC INFLAMMATORY INJURY, METAPLASIA, DYSPLASIA AND CANCERS OF EPITHELIAL TISSUES | UNIVERSITY OF HOUSTON SYSTEM (US) | 2022-06-30 | — | — | US | disclosed |
| EP-3962559-A1 | METHODS AND COMPOSITIONS FOR TREATING CHRONIC INFLAMMATORY INJURY, METAPLASIA, DYSPLASIA AND CANCERS OF EPITHELIAL TISSUES | University of Houston System (US) | 2022-03-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220202792-A1 | METHODS AND COMPOSITIONS FOR TREATING CHRONIC INFLAMMATORY INJURY, METAPLASIA, DYSPLASIA AND CANCERS OF EPITHELIAL TISSUES | FABP2, MUC1, FABP6 | RAB9A 2799/4885NPC1 3105/4885HCAR3 2698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.