Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | CCKBR | P32239 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
| ▸ | KDM5A | P29375 | 2/20 | 0.52 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3491650 | 1.00 | RAB9A (0.61) | RAB9ASMN1; SMN2NPC1GAAALDH1A1 | |
| SCHEMBL3490414 | 0.88 | SMN1; SMN2 (0.57) | RAB9ASMN1; SMN2NPC1GAAALDH1A1 | |
| SCHEMBL4657943 | 0.88 | FFAR1 (0.56) | RAB9ASMN1; SMN2NPC1GAAALDH1A1 | |
| SCHEMBL1767500 | 0.86 | SMN1; SMN2 (0.56) | RAB9ASMN1; SMN2NPC1GAAALDH1A1 | |
| SCHEMBL3492541 | 0.84 | MAPT (0.66) | RAB9ASMN1; SMN2NPC1GAAALDH1A1 | |
| SCHEMBL31240652 | 0.83 | LMNA (0.65) | RAB9ASMN1; SMN2NPC1GAAALDH1A1 | |
| SCHEMBL30367058 | 0.83 | RAB9A (0.61) | RAB9ASMN1; SMN2NPC1GAAALDH1A1 | |
| SCHEMBL2714016 | 0.81 | KDM4D (0.51) | RAB9ASMN1; SMN2NPC1ALDH1A1KDM5A | |
| SCHEMBL3493816 | 0.81 | TDP1 (0.52) | RAB9ASMN1; SMN2NPC1GAAALDH1A1 | |
| SCHEMBL7776518 | 0.81 | GAA (0.83) | RAB9ASMN1; SMN2NPC1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220202792-A1 | METHODS AND COMPOSITIONS FOR TREATING CHRONIC INFLAMMATORY INJURY, METAPLASIA, DYSPLASIA AND CANCERS OF EPITHELIAL TISSUES | UNIVERSITY OF HOUSTON SYSTEM (US) | 2022-06-30 | — | — | US | disclosed |
| EP-3962559-A1 | METHODS AND COMPOSITIONS FOR TREATING CHRONIC INFLAMMATORY INJURY, METAPLASIA, DYSPLASIA AND CANCERS OF EPITHELIAL TISSUES | University of Houston System (US) | 2022-03-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220202792-A1 | METHODS AND COMPOSITIONS FOR TREATING CHRONIC INFLAMMATORY INJURY, METAPLASIA, DYSPLASIA AND CANCERS OF EPITHELIAL TISSUES | FABP2, MUC1, FABP6 | RAB9A 2799/4885SMN1; SMN2 1456/4885NPC1 3105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.