Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | GSK3A | P49840 | 1/20 | 0.60 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.60 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | CCKBR | P32239 | 1/20 | 0.54 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240659 | 0.86 | RIOK2 (0.74) | RAB9AGSK3AMAPK10RIOK2MEN1 | |
| SCHEMBL29409190 | 0.83 | RAB9A (0.61) | LMNATSHRL3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL30367058 | 0.83 | RAB9A (0.61) | LMNATSHRL3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL3491650 | 0.83 | RAB9A (0.61) | LMNATSHRL3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL14156874 | 0.82 | LMNA (0.57) | LMNATSHRL3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL7415340 | 0.81 | GAA (0.61) | LMNATSHRL3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL7776518 | 0.81 | GAA (0.83) | LMNATSHRL3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL14156884 | 0.80 | RAB9A (0.57) | LMNATSHRL3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL3490414 | 0.80 | SMN1; SMN2 (0.57) | LMNATSHRL3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL14156892 | 0.80 | RAB9A (0.57) | LMNATSHRL3MBTL1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | disclosed |