Metochalcone

Metochalcone

SCHEMBL29412184

COc1ccc(C=CC(=O)c2ccc(OC)cc2OC)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 6/20 1.00
MAPT P10636 5/20 1.00
TNFRSF1A P19438 1/20 1.00
XDH P47989 1/20 0.86
MEN1 O00255 3/20 0.84
KMT2A Q03164 3/20 0.84
NPC1 O15118 1/20 0.84
RAB9A P51151 1/20 0.84
MAPK1 P28482 2/20 0.80
USP2 O75604 1/20 0.80
TLR9 Q9NR96 1/20 0.80
L3MBTL1 Q9Y468 1/20 0.80
FLT3 P36888 1/20 0.74
CYP3A4 P08684 3/20 0.74
LMNA P02545 1/20 0.74
APP P05067 1/20 0.74
CYP2C19 P33261 1/20 0.74
SMN1; SMN2 Q16637 1/20 0.74
PDE4A P27815 1/20 0.72
PDE4B Q07343 1/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Metochalcone SCHEMBL309111 1.00 ABCG2 (1.00) ABCG2MAPTTNFRSF1AXDHMEN1
Metochalcone SCHEMBL4957703 1.00 ABCG2 (1.00) ABCG2MAPTTNFRSF1AXDHMEN1
Metochalcone SCHEMBL29412185 1.00 ABCG2 (1.00) ABCG2MAPTTNFRSF1AXDHMEN1
SCHEMBL21527710 0.93 XDH (1.00) ABCG2MAPTTNFRSF1AXDHMEN1
SCHEMBL30138844 0.93 ABCG2 (0.89) ABCG2MAPTTNFRSF1AXDHMEN1
SCHEMBL21527708 0.93 XDH (1.00) ABCG2MAPTTNFRSF1AXDHMEN1
SCHEMBL29443572 0.92 ABCG2 (1.00) ABCG2MAPTTNFRSF1AXDHMEN1
SCHEMBL18742804 0.92 ABCG2 (0.86) ABCG2MAPTTNFRSF1AXDHMEN1
SCHEMBL4030793 0.91 MAPT (1.00) ABCG2MAPTTNFRSF1AXDHMEN1
SCHEMBL4030789 0.91 MAPT (1.00) ABCG2MAPTTNFRSF1AXDHMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4050417-B1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, ELECTROPHOTOGRAPHIC APPARATUS, AND METHOD OF MANUFACTURING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER CANON KK (JP) 2026-04-08 EP disclosed
US-12541157-B2 Electrophotographic photosensitive member, process cartridge, electrophotographic apparatus, and method of producing electrophotographic photosensitive member CANON KABUSHIKI KAISHA (JP) 2026-02-03 US disclosed
US-12523943-B2 Electrophotographic photosensitive member, process cartridge, electrophotographic apparatus, and method of producing electrophotographic photosensitive member CANON KABUSHIKI KAISHA (JP) 2026-01-13 US disclosed
US-12487536-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus, and method of producing electrophotographic photosensitive member CANON KABUSHIKI KAISHA (JP) 2025-12-02 US disclosed
US-12479778-B2 Plant food to enhance the nutritional value of pollen and nectar of plants to attract bees, butterflies and other pollinators MAIWALD DIANE (US) 2025-11-25 US disclosed
US-12416871-B2 Electrophotographic photosensitive member, process cartridge, electrophotographic apparatus, and method of manufacturing electrophotographic photosensitive member CANON KABUSHIKI KAISHA (JP) 2025-09-16 US disclosed
US-20250197307-A1 Plant Food to Enhance the Nutritional Value of Pollen and Nectar of Plants to Attract Bees, Butterflies and Other Pollinators MAIWALD DIANE (US) 2025-06-19 US disclosed
EP-4557006-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2025-05-21 EP disclosed
EP-4557007-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2025-05-21 EP disclosed
US-20250155830-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2025-05-15 US disclosed
EP-3191497-B1 BORON-BRIDGED 2-INDENYL METALLOCENE COMPLEXES FOR OLEFIN POLYMERIZATION SABIC GLOBAL TECHNOLOGIES BV (NL) 2023-05-03 EP disclosed
US-20230105110-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS, AND METHOD OF PRODUCING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER CANON KABUSHIKI KAISHA (JP) 2023-04-06 US disclosed
EP-4155824-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS, AND METHOD OF PRODUCING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER Canon Kabushiki Kaisha (JP) 2023-03-29 EP disclosed
US-11542267-B2 Cryptate compounds AUSTRALIAN NUCLEAR SCIENCE AND TECHNOLOGY ORGANISATION (AU) 2023-01-03 US disclosed
US-11535623-B2 Cryptate compounds AUSTRALIAN NUCLEAR SCIENCE AND TECHNOLOGY ORGANISATION (AU) 2022-12-27 US disclosed
US-20220283522-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, ELECTROPHOTOGRAPHIC APPARATUS, AND METHOD OF MANUFACTURING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER CANON KABUSHIKI KAISHA (JP) 2022-09-08 US disclosed
EP-4050417-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, ELECTROPHOTOGRAPHIC APPARATUS, AND METHOD OF MANUFACTURING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER CANON KABUSHIKI KAISHA (JP) 2022-08-31 EP disclosed
CN-114967383-A Electrophotographic photosensitive member, process cartridge, electrophotographic apparatus, and method of manufacturing electrophotographic photosensitive member 佳能株式会社 2022-08-30 CN disclosed
EP-3027631-B1 PROCESS FOR THE PREPARATION OF BRIDGED METALLOCENE COMPLEXES SUITABLE FOR USE IN OLEFIN POLYMERIZATION SAUDI BASIC IND CORP (SA) 2022-08-24 EP disclosed
US-20220067249-A1 Machine Learning to Accelerate Design of Energetic Materials IMAGARS LLC (US) 2022-03-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11542267-B2 Cryptate compounds HCCS, SQOR, NQO1 ABCG2 866/4885MAPT 3255/4885TNFRSF1A 4843/4885
US-11535623-B2 Cryptate compounds HCCS, SQOR, NQO1 ABCG2 866/4885MAPT 3255/4885TNFRSF1A 4843/4885
US-12541157-B2 Electrophotographic photosensitive member, process cartridge, electrophotographic apparatus, and method of producing electrophotographic photosensitive member PFN1, FRG1, AFF1 ABCG2 1616/4885MAPT 1993/4885TNFRSF1A 1035/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.