Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 2/20 | 0.63 |
| ▸ | JUN | P05412 | 1/20 | 0.63 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.63 |
| ▸ | CA1 | P00915 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | CA4 | P22748 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | BCHE | P06276 | 1/20 | 0.56 |
| ▸ | GUSB | P08236 | 1/20 | 0.56 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALPL | P05186 | 1/20 | 0.49 |
| ▸ | ALPI | P09923 | 1/20 | 0.49 |
| ▸ | ALPG | P10696 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4254014 | 1.00 | NFKB1 (0.63) | NFKB1JUNNFE2L2CA1CA2 | |
| SCHEMBL12425714 | 1.00 | NFKB1 (0.63) | NFKB1JUNNFE2L2CA1CA2 | |
| SCHEMBL12426301 | 0.83 | HDAC8 (0.66) | NFKB1JUNNFE2L2CA1CA2 | |
| SCHEMBL14244199 | 0.83 | HDAC8 (0.66) | NFKB1JUNNFE2L2CA1CA2 | |
| SCHEMBL17305570 | 0.81 | MAPT (0.65) | NFKB1JUNNFE2L2CA1CA2 | |
| SCHEMBL9444501 | 0.81 | MAPT (0.65) | NFKB1JUNNFE2L2CA1CA2 | |
| SCHEMBL1562801 | 0.81 | MAPT (0.65) | NFKB1JUNNFE2L2CA1CA2 | |
| SCHEMBL765999 | 0.79 | NFKB1 (0.70) | NFKB1JUNNFE2L2CA1CA2 | |
| SCHEMBL3508748 | 0.79 | NFKB1 (0.70) | NFKB1JUNNFE2L2CA1CA2 | |
| SCHEMBL8687395 | 0.79 | NFKB1 (0.70) | NFKB1JUNNFE2L2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4204401-A1 | COMPOUNDS FOR AND METHODS OF TREATING DISEASES | Alterity Therapeutics Limited (AU) | 2023-07-05 | — | — | EP | disclosed |
| WO-2022040747-A1 | COMPOUNDS FOR AND METHODS OF TREATING DISEASES | Alterity Therapeutics Limited (AU) | 2022-03-03 | — | — | WO | disclosed |