Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 2/20 | 0.63 |
| ▸ | JUN | P05412 | 1/20 | 0.63 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.63 |
| ▸ | CA1 | P00915 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | CA4 | P22748 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | BCHE | P06276 | 1/20 | 0.56 |
| ▸ | GUSB | P08236 | 1/20 | 0.56 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALPL | P05186 | 1/20 | 0.49 |
| ▸ | ALPI | P09923 | 1/20 | 0.49 |
| ▸ | ALPG | P10696 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29412622 | 1.00 | NFKB1 (0.63) | NFKB1JUNNFE2L2CA1CA2 | |
| SCHEMBL12425714 | 1.00 | NFKB1 (0.63) | NFKB1JUNNFE2L2CA1CA2 | |
| SCHEMBL12426301 | 0.83 | HDAC8 (0.66) | NFKB1JUNNFE2L2CA1CA2 | |
| SCHEMBL14244199 | 0.83 | HDAC8 (0.66) | NFKB1JUNNFE2L2CA1CA2 | |
| SCHEMBL17305570 | 0.81 | MAPT (0.65) | NFKB1JUNNFE2L2CA1CA2 | |
| SCHEMBL9444501 | 0.81 | MAPT (0.65) | NFKB1JUNNFE2L2CA1CA2 | |
| SCHEMBL1562801 | 0.81 | MAPT (0.65) | NFKB1JUNNFE2L2CA1CA2 | |
| SCHEMBL765999 | 0.79 | NFKB1 (0.70) | NFKB1JUNNFE2L2CA1CA2 | |
| SCHEMBL3508748 | 0.79 | NFKB1 (0.70) | NFKB1JUNNFE2L2CA1CA2 | |
| SCHEMBL8687395 | 0.79 | NFKB1 (0.70) | NFKB1JUNNFE2L2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112402436-A | Diagnosis and treatment integrated fluorescent drug molecule based on adriamycin drug and preparation and application thereof | 大连大学 | 2021-02-26 | — | — | CN | claimed |
| CN-119208610-B | Water-based zinc ion battery negative electrode coating material, and preparation method and application thereof | 大连大学 | 2025-12-26 | — | — | CN | disclosed |
| CN-120247980-A | Ruthenium complex photosensitizer modified by coumarin hydrazide condensate for photocatalytic hydrogen production and preparation method thereof | 河南牧业经济学院 | 2025-07-04 | — | — | CN | disclosed |
| CN-120247980-A | Ruthenium complex photosensitizer modified by coumarin hydrazide condensate for photocatalytic hydrogen production and preparation method thereof | 河南牧业经济学院 | 2025-07-04 | — | — | CN | disclosed |
| EP-3458855-B1 | ASSAY FOR DETERMINING THE TOTAL CARBONYLATION LEVEL ON A POLYPEPTIDE | GENENTECH INC (US) | 2025-04-30 | — | — | EP | disclosed |
| CN-119208610-A | Water-based zinc ion battery negative electrode coating material, and preparation method and application thereof | 大连大学 | 2024-12-27 | — | — | CN | disclosed |
| CN-119208610-A | Water-based zinc ion battery negative electrode coating material, and preparation method and application thereof | 大连大学 | 2024-12-27 | — | — | CN | disclosed |
| CN-117126139-A | Colorimetric copper ion fluorescent probe and synthesis and application thereof | 南通大学 | 2023-11-28 | — | — | CN | disclosed |
| WO-2023027654-A1 | CARBOXYLIC ACID HYDRAZIDE-COUMARINE HYBRID COMPOUNDS ANTIINFLAMMATORY AND ANTICONVULSANE AGENT | CUKUROVA UNIVERSITESI REKTORLUGU (TR) | 2023-03-02 | — | — | WO | disclosed |
| US-11371999-B2 | Assay for determining the total carbonylation level on a polypeptide | UNIVERSITY OF KANSAS (US) | 2022-06-28 | — | — | US | disclosed |
| US-20030096765-A1 | Prodrugs activated by targeted catalytic proteins | IGEN, INC. | 2003-05-22 | — | — | US | disclosed |
| US-6258360-B1 | BENZOATE CONJUGATES; ANTITUMOR AGENTS | IGEN INTERNATIONAL, INC. | 2001-07-10 | — | — | US | disclosed |
| EP-0746336-A1 | PRODRUGS ACTIVATED BY TARGETED CATALYTIC PROTEINS | IGEN, INC. (US) | 1996-12-11 | — | — | EP | disclosed |
| EP-0746336-A4 | PRODRUGS ACTIVATED BY TARGETED CATALYTIC PROTEINS | IGEN INC (US) | 1996-07-26 | — | — | EP | disclosed |
| US-5403711-A | Nucleic acid hybridization and amplification method for detection of specific sequences in which a complementary labeled nucleic acid probe is cleaved | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 1995-04-04 | — | — | US | disclosed |
| EP-0365627-B1 | CATALYTIC HYBRIDIZATION SYSTEMS FOR THE DETECTION OF NUCLEIC ACID SEQUENCES BASED ON THEIR ACTIVITY AS COFACTORS IN CATALYTIC REACTIONS IN WHICH A COMPLEMENTARY LABELED NUCLEIC ACID PROBE IS CLEAVED | UNIV IOWA RES FOUND (US) | 1993-12-22 | — | — | EP | disclosed |
| WO-1993002703-A1 | PRODRUGS ACTIVATED BY TARGETED CATALYTIC PROTEINS | IGEN, INC. (US) | 1993-02-18 | — | — | WO | disclosed |
| EP-0365627-A4 | CATALYTIC HYBRIDIZATION SYSTEMS FOR THE DETECTION OF NUCLEIC ACID SEQUENCES BASED ON THEIR ACTIVITY AS COFACTORS IN CATALYTIC REACTIONS IN WHICH A COMPLEMENTARY LABELED NUCLEIC ACID PROBE IS CLEAVED | — | 1990-10-10 | — | — | EP | disclosed |
| EP-0365627-A1 | CATALYTIC HYBRIDIZATION SYSTEMS FOR THE DETECTION OF NUCLEIC ACID SEQUENCES BASED ON THEIR ACTIVITY AS COFACTORS IN CATALYTIC REACTIONS IN WHICH A COMPLEMENTARY LABELED NUCLEIC ACID PROBE IS CLEAVED. | UNIV IOWA RES FOUND (US) | 1990-05-02 | — | — | EP | disclosed |
| WO-1989009284-A1 | CATALYTIC HYBRIDIZATION SYSTEMS FOR THE DETECTION OF NUCLEIC ACID SEQUENCES BASED ON THEIR ACTIVITY AS COFACTORS IN CATALYTIC REACTIONS IN WHICH A COMPLEMENTARY LABELED NUCLEIC ACID PROBE IS CLEAVED | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 1989-10-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030096765-A1 | Prodrugs activated by targeted catalytic proteins | DNPH1, DNPEP, PNP | NFKB1 2558/4885JUN 2046/4885NFE2L2 4016/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.