Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | CFTR | P13569 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | PRKCI | P41743 | 2/20 | 0.54 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL167456 | 1.00 | NAPRT (0.61) | NAPRTALDH1A1CFTRHSD17B10TDP1 | |
| Hydrochloric Acid SCHEMBL29373852 | 0.98 | NAPRT (0.59) | NAPRTALDH1A1CFTRHSD17B10TDP1 | |
| SCHEMBL30753027 | 0.88 | NAPRT (0.56) | NAPRTALDH1A1CFTRHSD17B10TDP1 | |
| SCHEMBL219458 | 0.85 | NAPRT (0.66) | NAPRTALDH1A1TDP1PRKCIKDM4E | |
| SCHEMBL27958777 | 0.83 | NAPRT (0.63) | NAPRTALDH1A1TDP1PRKCIKDM4E | |
| SCHEMBL812065 | 0.81 | KDM4E (0.59) | ALDH1A1CFTRHSD17B10TDP1MAP2K1 | |
| SCHEMBL29923922 | 0.81 | NAPRT (0.56) | NAPRTALDH1A1HSD17B10TDP1PRKCI | |
| SCHEMBL1292847 | 0.81 | NAPRT (0.56) | NAPRTALDH1A1HSD17B10TDP1PRKCI | |
| SCHEMBL12517053 | 0.81 | NAPRT (0.56) | NAPRTALDH1A1PRKCIKDM4EPOLB | |
| SCHEMBL181049 | 0.81 | ALDH1A1 (0.60) | NAPRTALDH1A1HSD17B10KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4214208-A1 | COMPOUNDS WHICH INHIBIT RNA POLYMERASE | The Johns Hopkins University (US) | 2023-07-26 | — | — | EP | disclosed |
| WO-2022060799-A1 | COMPOUNDS WHICH INHIBIT RNA POLYMERASE AND THEIR USE | THE JOHNS HOPKINS UNIVERSITY (US) | 2022-03-24 | — | — | WO | disclosed |
| WO-2022060805-A1 | COMPOUNDS WHICH INHIBIT RNA POLYMERASE | THE JOHNS HOPKINS UNIVERSITY (US) | 2022-03-24 | — | — | WO | disclosed |