SCHEMBL167456

SCHEMBL167456

COC(=O)c1cccnc1N

nearest known ligand 0.61

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NAPRT Q6XQN6 1/20 0.61
ALDH1A1 P00352 3/20 0.56
CFTR P13569 1/20 0.56
HSD17B10 Q99714 1/20 0.56
TDP1 Q9NUW8 1/20 0.55
PRKCI P41743 2/20 0.54
MAP2K1 Q02750 1/20 0.53
KDM4E B2RXH2 6/20 0.51
POLB P06746 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
PKM P14618 1/20 0.50
ATM Q13315 1/20 0.50
GLA P06280 1/20 0.50
GAA P10253 1/20 0.50
LMNA P02545 1/20 0.48
TSHR P16473 1/20 0.48
CNR2 P34972 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29412876 1.00 NAPRT (0.61) NAPRTALDH1A1CFTRHSD17B10TDP1
Hydrochloric Acid SCHEMBL29373852 0.98 NAPRT (0.59) NAPRTALDH1A1CFTRHSD17B10TDP1
SCHEMBL30753027 0.88 NAPRT (0.56) NAPRTALDH1A1CFTRHSD17B10TDP1
SCHEMBL219458 0.85 NAPRT (0.66) NAPRTALDH1A1TDP1PRKCIKDM4E
SCHEMBL27958777 0.83 NAPRT (0.63) NAPRTALDH1A1TDP1PRKCIKDM4E
SCHEMBL812065 0.81 KDM4E (0.59) ALDH1A1CFTRHSD17B10TDP1MAP2K1
SCHEMBL29923922 0.81 NAPRT (0.56) NAPRTALDH1A1HSD17B10TDP1PRKCI
SCHEMBL1292847 0.81 NAPRT (0.56) NAPRTALDH1A1HSD17B10TDP1PRKCI
SCHEMBL12517053 0.81 NAPRT (0.56) NAPRTALDH1A1PRKCIKDM4EPOLB
SCHEMBL181049 0.81 ALDH1A1 (0.60) NAPRTALDH1A1HSD17B10KDM4EL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 665 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113649055-B Catalyst for selective hydrogenation of methyl picolinate and preparation method and application thereof 湖北大学 2023-03-24 CN claimed
CN-113649055-A Catalyst for selective hydrogenation of methyl picolinate and preparation method and application thereof 湖北大学 2021-11-16 CN claimed
CN-101701031-A Polypeptide condensing agent and synthesis method thereof CHANGZHOU NANJING UNIVERSITY H 2010-05-05 CN claimed
CN-122071467-A Imidazo nitrogen heteroaryl oxazoline compound and preparation method and application thereof 贵州大学 2026-05-22 CN disclosed
US-12630528-B2 Amino aryl derivative useful as diacylglycerol acyltransferase 2 inhibitor and use thereof LG CHEM, LTD. (KR) 2026-05-19 US disclosed
CN-115835909-B Cannabinoid receptor type 2 (CB 2) modulators and uses thereof 泰昂治疗公司 2026-05-15 CN disclosed
CN-121673283-A Pyridopyrimidinone derivative and preparation method and application thereof 江苏海洋大学 2026-03-17 CN disclosed
EP-4665339-A1 INHIBITING ALPHA V BETA 8 INTEGRIN Morphic Therapeutic, Inc. (US) 2025-12-24 EP disclosed
US-12492207-B2 Compounds, pharmaceutical formulations, and methods for treatment of cancer THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE OF NEW YORK (US) 2025-12-09 US disclosed
US-20250326746-A1 EIF4E INHIBITORS AND USES THEREOF PIC Therapeutics, Inc. 2025-10-23 US disclosed
US-12421243-B2 Pharmaceutically effective compounds inhibiting selectively the myosin 2 isoforms PRINTNET KERESKEDELMI ÉS SZOLGÁLTATÓ KFT. (HU) 2025-09-23 US disclosed
US-4128551-A HERBICIDE THE DOW CHEMICAL CO. (US) 1978-12-05 US disclosed
US-4098792-A HERBICIDES THE DOW CHEMICAL COMPANY (US) 1978-07-04 US disclosed
US-4085279-A HERBICIDES THE DOW CHEMICAL COMPANY (US) 1978-04-18 US disclosed
US-4085278-A HERBICIDES THE DOW CHEMICAL COMPANY (US) 1978-04-18 US disclosed
US-4082758-A HERBICIDES THE DOW CHEMICAL COMPANY (US) 1978-04-04 US disclosed
US-4082759-A HERBICIDES THE DOW CHEMICAL COMPANY (US) 1978-04-04 US disclosed
US-4058533-A HERBICIDES THE DOW CHEMICAL COMPANY (US) 1977-11-15 US disclosed
US-4014888-A HERBICIDES THE DOW CHEMICAL COMPANY (US) 1977-03-29 US disclosed
US-3989507-A HERBICIDES THE DOW CHEMICAL COMPANY (US) 1976-11-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12492207-B2 Compounds, pharmaceutical formulations, and methods for treatment of cancer GAK, CCNK, CDK1 NAPRT 2822/4885ALDH1A1 4510/4885CFTR 4828/4885
US-20250326746-A1 EIF4E INHIBITORS AND USES THEREOF EIF4E, EIF4EBP1, EIF4A1 NAPRT 2953/4885ALDH1A1 4776/4885CFTR 4043/4885
US-12421243-B2 Pharmaceutically effective compounds inhibiting selectively the myosin 2 isoforms MYH2, MYLK2, MYO1B NAPRT 3389/4885ALDH1A1 2854/4885CFTR 1525/4885
US-12630528-B2 Amino aryl derivative useful as diacylglycerol acyltransferase 2 inhibitor and use thereof DGAT2, DGAT1, SOAT2 NAPRT 1108/4885ALDH1A1 597/4885CFTR 2553/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.