Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA5A | P35218 | 1/20 | 0.51 |
| ▸ | GPR17 | Q13304 | 10/20 | 0.51 |
| ▸ | P2RY2 | P41231 | 6/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8690576 | 0.98 | TSHR (0.53) | KMT2AGAAHTTTSHRLMNA | |
| SCHEMBL28701811 | 0.97 | TSHR (0.52) | KMT2AGAAHTTTSHRLMNA | |
| SCHEMBL7123260 | 0.84 | TSHR (0.57) | KMT2AGAAHTTTSHRLMNA | |
| SCHEMBL14596864 | 0.84 | GPR17 (0.49) | KMT2AGAAHTTTSHRLMNA | |
| SCHEMBL8966976 | 0.83 | CHRNB2 (0.54) | KMT2AGAAHTTTSHRLMNA | |
| SCHEMBL4838474 | 0.81 | GPR17 (0.72) | TSHRGPR17P2RY2ACHE | |
| SCHEMBL31572348 | 0.81 | GPR17 (0.72) | TSHRGPR17P2RY2ACHE | |
| SCHEMBL7145541 | 0.81 | TSHR (0.53) | KMT2AGAAHTTTSHRLMNA | |
| SCHEMBL9005003 | 0.81 | GPR17 (0.55) | KMT2AGAAHTTTSHRLMNA | |
| SCHEMBL22462541 | 0.81 | TSHR (0.53) | KMT2AGAAHTTTSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114085214-A | Sofantinib impurity and preparation method and application thereof | 和记黄埔医药（上海）有限公司 | 2022-02-25 | — | — | CN | claimed |