Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | GPR17 | Q13304 | 10/20 | 0.49 |
| ▸ | P2RY2 | P41231 | 4/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA5A | P35218 | 1/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7123260 | 0.86 | TSHR (0.57) | TSHRLMNAGAAHTTKMT2A | |
| SCHEMBL22462541 | 0.83 | TSHR (0.53) | TSHRLMNAGAAHTTKMT2A | |
| SCHEMBL8690576 | 0.83 | TSHR (0.53) | TSHRLMNAGAAHTTKMT2A | |
| SCHEMBL9005003 | 0.83 | GPR17 (0.55) | TSHRLMNAGAAHTTKMT2A | |
| SCHEMBL9451297 | 0.83 | CA2 (0.64) | TSHRLMNAGAAHTTKMT2A | |
| SCHEMBL9000083 | 0.83 | GPR17 (0.55) | TSHRLMNAGAAHTTKMT2A | |
| SCHEMBL17675159 | 0.83 | TSHR (0.53) | TSHRLMNAGAAHTTKMT2A | |
| Methane SCHEMBL27556231 | 0.82 | TSHR (0.50) | TSHRLMNAGAAHTTKMT2A | |
| SCHEMBL8966976 | 0.81 | CHRNB2 (0.54) | TSHRLMNAGAAHTTKMT2A | |
| SCHEMBL28701811 | 0.81 | TSHR (0.52) | TSHRLMNAGAAHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2931703-B1 | METHOD FOR PRODUCING BIS (3-AMINOPHENYL) DISULFIDES AND 3-AMINOTHIOLS | BAYER CROPSCIENCE AG (DE) | 2018-11-28 | — | — | EP | claimed |
| EP-2931703-B1 | METHOD FOR PRODUCING BIS (3-AMINOPHENYL) DISULFIDES AND 3-AMINOTHIOLS | BAYER CROPSCIENCE AG (DE) | 2018-11-28 | — | — | EP | disclosed |
| EP-2931703-A1 | METHOD FOR PRODUCING BIS(3-AMINOPHENYL)DISULFIDES AND 3-AMINOTHIOLS | Bayer CropScience AG (DE) | 2015-10-21 | — | — | EP | disclosed |
| WO-2014090913-A1 | METHOD FOR PRODUCING BIS(3-AMINOPHENYL)DISULFIDES AND 3-AMINOTHIOLS | BAYER CROPSCIENCE AG (DE) | 2014-06-19 | — | — | WO | disclosed |
| EP-0928790-B1 | Thiazole derivatives | HOFFMANN LA ROCHE (CH) | 2003-03-05 | — | — | EP | disclosed |
| US-6344562-B1 | ANTITUMOR AGENTS | HOFFMANN-LA ROCHE INC. | 2002-02-05 | — | — | US | disclosed |
| US-20020010316-A1 | Thiazole derivatives | ALIG LEO (CH) | 2002-01-24 | — | — | US | disclosed |
| US-6320054-B1 | INHIBIT BINDING OF ADHESIVE PROTEINS TO THE SURFACE OF DIFFERENT TYPES F CELL AND ACCORDINGLY INFLUENCE CELL-CELL AND CELL-MATRIX INTERACTIONS. | HOFFMAN-LA ROCHE INC. | 2001-11-20 | — | — | US | disclosed |
| US-6100282-A | Thiazole derivatives | HOFFMAN-LA ROCHE INC. (US) | 2000-08-08 | — | — | US | disclosed |
| EP-0928790-A1 | Thiazole derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1999-07-14 | — | — | EP | disclosed |
| US-5436370-A | From nitrobenzene, chlorosulfonic acid, thionyl chloride | HOECHST AG (DE) | 1995-07-25 | — | — | US | disclosed |
| US-5086128-A | HIGH MOLECULAR WEIGHT ARYLENE SULPHIDE POLYMER MELT MIXED WITH AROMATIC NITRO COMPOUND | BAYER AKTIENGESELLSCHAFT (DE) | 1992-02-04 | — | — | US | disclosed |
| WO-1991013863-A1 | METHOD FOR PREPARING 3-NITROBENZENE SULPHONIC ACID CHLORIDE | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-09-19 | — | — | WO | disclosed |
| US-4656290-A | Process for preparing thio, dithio or carbonyl compounds | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1987-04-07 | — | — | US | disclosed |
| EP-0093363-B1 | PROCESS FOR THE PREPARATION OF DISULPHIDES | CASSELLA Aktiengesellschaft (DE) | 1987-01-14 | — | — | EP | disclosed |
| US-4587275-A | AROMATIC DIAMINE WITH SULFONIC ACID GROUP AS CHAIN EXTENSION AGENT | BAYER AKTIENGESELLSCHAFT (DE) | 1986-05-06 | — | — | US | disclosed |
| EP-0093363-A1 | Process for the preparation of disulphides | CASSELLA Aktiengesellschaft (DE) | 1983-11-09 | — | — | EP | disclosed |
| US-4388246-A | THERMAL SPLITTING OF CARBAMATES | BAYER AKTIENGESELLSCHAFT (DE) | 1983-06-14 | — | — | US | disclosed |
| US-4368260-A | Photographic light sensitive element | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1983-01-11 | — | — | US | disclosed |
| US-4195992-A | AZO DYE | AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) | 1980-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020010316-A1 | Thiazole derivatives | VCAM1, SOST, TGFB1 | TSHR 166/4885LMNA 3184/4885GAA 4036/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.