Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.54 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | GPR17 | Q13304 | 7/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27717822 | 0.89 | CHRNB2 (0.50) | CHRNB2CHRNA4TSHRLMNAKMT2A | |
| SCHEMBL11979485 | 0.85 | LMNA (0.50) | CHRNB2CHRNA4TSHRLMNAKMT2A | |
| SCHEMBL8690576 | 0.85 | TSHR (0.53) | CHRNB2CHRNA4TSHRLMNAKMT2A | |
| SCHEMBL7123260 | 0.84 | TSHR (0.57) | CHRNB2CHRNA4TSHRLMNAKMT2A | |
| Methane SCHEMBL27556231 | 0.84 | TSHR (0.50) | CHRNB2CHRNA4TSHRLMNAKMT2A | |
| SCHEMBL28701811 | 0.83 | TSHR (0.52) | CHRNB2CHRNA4TSHRLMNAKMT2A | |
| SCHEMBL29413045 | 0.83 | KMT2A (0.54) | CHRNB2CHRNA4TSHRLMNAKMT2A | |
| SCHEMBL9005003 | 0.81 | GPR17 (0.55) | TSHRLMNAKMT2AHTTGAA | |
| SCHEMBL9451297 | 0.81 | CA2 (0.64) | CHRNB2CHRNA4TSHRLMNAKMT2A | |
| SCHEMBL17675159 | 0.81 | TSHR (0.53) | CHRNB2CHRNA4TSHRLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0659184-B1 | OPTICALLY ACTIVE HYDROQUININE (AMINO-3 PHENYL)-1 ETHANESULFONATE, PREPARATION AND USE THEREOF | RHONE POULENC RORER SA (FR) | 1996-02-28 | — | — | EP | claimed |
| CN-114751920-B | Antitumor compounds | 法马马有限公司 | 2024-06-07 | — | — | CN | disclosed |
| CN-114736219-B | Antitumor compounds | 法马马有限公司 | 2024-06-07 | — | — | CN | disclosed |
| CN-118139851-A | Antitumor compounds | 法马马有限公司 | 2024-06-04 | — | — | CN | disclosed |
| CN-111556872-B | Synthesis of borate derivatives and uses thereof | 梅琳塔治疗公司 | 2024-05-10 | — | — | CN | disclosed |
| CN-117986153-A | Ionizable cationic lipid compound, and preparation method and application thereof | 晟迪生物医药(苏州)有限公司 | 2024-05-07 | — | — | CN | disclosed |
| CN-117865987-A | Antitumor compounds | 法马马有限公司 | 2024-04-12 | — | — | CN | disclosed |
| CN-114615999-B | Drug antibody conjugates | 法马马有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-110650954-B | anticancer compounds | 法马马有限公司 | 2023-11-03 | — | — | CN | disclosed |
| CN-113226377-B | Antibody drug conjugates comprising an eltrinastine derivative | 法马马有限公司 | 2022-10-18 | — | — | CN | disclosed |
| CN-114751920-A | Antitumor compounds | 法马马有限公司 | 2022-07-15 | — | — | CN | disclosed |
| CN-114736219-A | Antitumor compounds | 法马马有限公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-114615999-A | Drug antibody conjugates | 法马马有限公司 | 2022-06-10 | — | — | CN | disclosed |
| CN-113166102-A | Anticancer compounds | 法马马有限公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-110650954-A | Anticancer compounds | 法马马有限公司 | 2020-01-03 | — | — | CN | disclosed |
| CN-110621678-A | Antitumor compounds | 法马马有限公司 | 2019-12-27 | — | — | CN | disclosed |
| CN-105555759-A | Compounds with antibacterial activity | FUND MEDINA CT DE EXCELENCIA EN INVESTIG DE MEDICAMENTOS INNOVADORES EN ANDALUCIA | 2016-05-04 | — | — | CN | disclosed |
| CN-103038240-A | Synthetic method for preparing ecteinascidin compounds | PHARMA MAR SA | 2013-04-10 | — | — | CN | disclosed |