SCHEMBL29414010

SCHEMBL29414010

O=C(O)C1C(c2ccc(F)c(C(F)(F)F)c2)C1(Cl)Cl

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 1/20 0.40
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
LMNA P02545 3/20 0.40
KMO O15229 2/20 0.36
AR P10275 1/20 0.36
ADRA2A P08913 1/20 0.36
CHRNB2 P17787 1/20 0.36
ADRA2C P18825 1/20 0.36
CHRNB4 P30926 1/20 0.36
CHRNA3 P32297 1/20 0.36
CHRNA7 P36544 1/20 0.36
CHRNA4 P43681 1/20 0.36
TMEM97 Q5BJF2 1/20 0.36
GRM4 Q14833 1/20 0.36
SLC9A1 P19634 3/20 0.35
TAS1R3 Q7RTX0 2/20 0.35
TAS1R1 Q7RTX1 2/20 0.35
TAS1R2 Q8TE23 2/20 0.35
ALDH1A1 P00352 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18146734 1.00 NOTUM (0.40) NOTUMMEN1KMT2ALMNAKMO
SCHEMBL18146739 1.00 NOTUM (0.40) NOTUMMEN1KMT2ALMNAKMO
SCHEMBL18146735 1.00 NOTUM (0.40) NOTUMMEN1KMT2ALMNAKMO
SCHEMBL20901183 1.00 NOTUM (0.40) NOTUMMEN1KMT2ALMNAKMO
SCHEMBL21021644 0.89 ADRA2A (0.39) NOTUMMEN1KMT2ALMNAAR
SCHEMBL18145938 0.89 KDM1A (0.43) NOTUMMEN1KMT2ALMNACHRNB2
SCHEMBL18145941 0.89 KDM1A (0.43) NOTUMMEN1KMT2ALMNACHRNB2
SCHEMBL18145943 0.89 KDM1A (0.43) NOTUMMEN1KMT2ALMNACHRNB2
SCHEMBL20076634 0.87 SLC9A1 (0.40) NOTUMMEN1KMT2ALMNAKMO
SCHEMBL30739761 0.87 SLC9A1 (0.40) NOTUMMEN1KMT2ALMNAKMO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250228239-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-07-17 US disclosed
CN-118044519-A Molecules having pesticidal utility, and intermediates, compositions and methods related thereto 科迪华农业科技有限责任公司 2024-05-17 CN disclosed
US-11944099-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto CORTEVA AGRISCIENCE LLC (US) 2024-04-02 US disclosed
CN-117603014-A Meta-diamide compounds for controlling invertebrate pests FMC公司 2024-02-27 CN disclosed
CN-110072842-B Molecules having pesticidal utility, and intermediates, compositions and methods related thereto 科迪华农业科技有限责任公司 2024-02-02 CN disclosed
EP-3964067-B1 COMPOSITION COMPRISING A MOLECULE HAVING PESTICIDAL UTILITY DOW AGROSCIENCES LLC (US) 2024-01-03 EP disclosed
EP-4139272-A1 PROCESSES RELATED TO FORMATION OF ARYLCYCLOPROPYL CARBOXYLIC ACIDS Corteva Agriscience LLC (US) 2023-03-01 EP disclosed
CN-109863131-B Method for preparing cyclopropanecarboxylic acid 美国陶氏益农公司 2022-04-05 CN disclosed
EP-3971166-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND COMPOSITIONS, AND PROCESSES, RELATED THERETO Corteva Agriscience LLC (US) 2022-03-23 EP disclosed
EP-3964067-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO Dow AgroSciences LLC (US) 2022-03-09 EP disclosed
EP-3964495-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND COMPOSITIONS, AND PROCESSES, RELATED THERETO Dow AgroSciences LLC (US) 2022-03-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11944099-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto ACHE, DDT, MLYCD NOTUM 5/4885MEN1 1180/4885KMT2A 2615/4885
US-20250228239-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO ACHE, DDT, MLYCD NOTUM 5/4885MEN1 1180/4885KMT2A 2615/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.