Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD4 | P01730 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22632693 | 1.00 | CD4 (0.31) | CD4ALDH1A1SMN1; SMN2 | |
| SCHEMBL28686236 | 0.91 | — | — | |
| SCHEMBL38661434 | 0.90 | — | — | |
| SCHEMBL31258414 | 0.84 | CD4 (0.42) | CD4ALDH1A1SMN1; SMN2 | |
| SCHEMBL22632786 | 0.84 | CD4 (0.42) | CD4ALDH1A1SMN1; SMN2 | |
| SCHEMBL22633271 | 0.78 | ALDH1A1 (0.31) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL22632665 | 0.77 | ALK (0.35) | ALDH1A1 | |
| SCHEMBL22632891 | 0.76 | L3MBTL1 (0.34) | ALDH1A1 | |
| SCHEMBL22632642 | 0.76 | PTGS2 (0.32) | SMN1; SMN2 | |
| SCHEMBL29414678 | 0.76 | PTGS2 (0.32) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3965884-A1 | MODULATORS OF THR-BETA AND METHODS OF USE THEREOF | Aligos Therapeutics, Inc. (US) | 2022-03-16 | — | — | EP | disclosed |