SCHEMBL29414769

SCHEMBL29414769

Cc1ccc(S(=O)(=O)n2cc(C(C)C)c3nc(Cc4c(C)cc(B5OC(C)(C)C(C)(C)O5)cc4C)cnc32)cc1

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22633321 1.00 L3MBTL1 (0.30) L3MBTL1
SCHEMBL22632775 0.87 HTR6 (0.32)
SCHEMBL22632891 0.84 L3MBTL1 (0.34) L3MBTL1
SCHEMBL22632665 0.84 ALK (0.35) L3MBTL1
SCHEMBL29414832 0.83 PDE4A (0.34) L3MBTL1
SCHEMBL22632787 0.83 PDE4A (0.34) L3MBTL1
SCHEMBL22632745 0.82 L3MBTL1 (0.32) L3MBTL1
SCHEMBL22638209 0.81 PDE4A (0.35) L3MBTL1
SCHEMBL22632642 0.79 PTGS2 (0.32) L3MBTL1
SCHEMBL29414678 0.79 PTGS2 (0.32) L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3965884-A1 MODULATORS OF THR-BETA AND METHODS OF USE THEREOF Aligos Therapeutics, Inc. (US) 2022-03-16 EP disclosed