Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | BLM | P54132 | 1/20 | 0.67 |
| ▸ | AGER | Q15109 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29559479 | 1.00 | KDM4E (0.67) | KDM4EALDH1A1L3MBTL1NPSR1CYP3A4 | |
| SCHEMBL29416324 | 0.89 | L3MBTL1 (0.62) | KDM4EALDH1A1L3MBTL1NPSR1CYP3A4 | |
| SCHEMBL69990 | 0.89 | L3MBTL1 (0.62) | KDM4EALDH1A1L3MBTL1NPSR1CYP3A4 | |
| SCHEMBL519095 | 0.86 | KDM4E (0.67) | KDM4EALDH1A1L3MBTL1NPSR1CYP3A4 | |
| SCHEMBL30503698 | 0.86 | KDM4E (0.67) | KDM4EALDH1A1L3MBTL1NPSR1CYP3A4 | |
| SCHEMBL9632137 | 0.86 | L3MBTL1 (0.58) | KDM4EALDH1A1L3MBTL1NPSR1CYP3A4 | |
| SCHEMBL311087 | 0.85 | KDM4E (0.71) | KDM4EALDH1A1L3MBTL1NPSR1CYP3A4 | |
| SCHEMBL7367762 | 0.84 | L3MBTL1 (0.50) | KDM4EALDH1A1L3MBTL1NPSR1CYP3A4 | |
| SCHEMBL7362858 | 0.84 | KDM4E (0.56) | KDM4EALDH1A1L3MBTL1NPSR1CYP3A4 | |
| SCHEMBL2372518 | 0.84 | L3MBTL1 (0.57) | KDM4EALDH1A1L3MBTL1NPSR1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 213 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109705116-A | A kind of synthetic method of 6- benzyl-pyrrole simultaneously [3,4-b] pyridine | 赵明 | 2019-05-03 | — | — | CN | claimed |
| CN-109503823-A | A kind of low temperature curing type polyester resin and the preparation method and application thereof | 黄山学院 | 2019-03-22 | — | — | CN | claimed |
| CN-104363887-B | Compositions, methods and uses comprising pyridine dicarboxylic acid esters and esters of glucose and fatty acids | 莱雅公司 | 2017-11-10 | — | — | CN | claimed |
| CN-107106452-A | Specific pyridinedicarboxylicacid acid derivatives/antioxidant combination | 欧莱雅 | 2017-08-29 | — | — | CN | claimed |
| CN-106587318-A | High-efficiency heavy metal waste water treating agent | 余姚市益群机械厂 | 2017-04-26 | — | — | CN | claimed |
| EP-1327630-B1 | NEW DERIVATIVES OF CYANO-ARYL (OR CYANOHETEROARYL)-CARBONYL-PIPERAZINYL-PYRIMIDINES, THEIR PREPARATION AND APPLICATION AS MEDICATION | ESTEVE LABOR DR (ES) | 2007-12-12 | — | — | EP | claimed |
| US-7300937-B2 | Derivatives of cyano-aryl (or cyanoheteroaryl)-carbonyl-piperazinyl-pyrimidines, their preparation and application as medication | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2007-11-27 | — | — | US | claimed |
| US-20040048872-A1 | New derivatives of cyano-aryl (or cyanoheteroaryl) -carbonyl- piperazinyl - pyrimidines, their preparation and application as medication | LABORATORIES DEL DR. ESTEVE, S.A. (ES) | 2004-03-11 | — | — | US | claimed |
| EP-1327630-A1 | NEW DERIVATIVES OF CYANO-ARYL (OR CYANOHETEROARYL)-CARBONYL-PIPERAZINYL-PYRIMIDINES, THEIR PREPARATION AND APPLICATION AS MEDICATION | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2003-07-16 | — | — | EP | claimed |
| EP-4126832-B1 | MODULATORS OF HEMOGLOBIN | GLOBAL BLOOD THERAPEUTICS INC (US) | 2026-01-07 | — | — | EP | disclosed |
| US-12378254-B2 | Disubstituted octahydropyrrolo[3,4-c]pyrroles as orexin receptor modulators | JANSSEN PHARMACEUTICA NV (BE) | 2025-08-05 | — | — | US | disclosed |
| EP-4541422-A2 | QUINOLINE DERIVATIVES AS ALPHA4BETA7 INTEGRIN INHIBITORS | Gilead Sciences, Inc. (US) | 2025-04-23 | — | — | EP | disclosed |
| US-20250032473-A1 | QUINOLINE DERIVATIVES | GILEAD SCIENCES, INC. | 2025-01-30 | — | — | US | disclosed |
| CN-113563244-B | Substituted aza five-membered ring compound and application thereof in medicine | 广东东阳光药业股份有限公司 | 2025-01-10 | — | — | CN | disclosed |
| US-4525555-A | TITANIUM COMPOUND SUPPORTED ON SOLID REACTION PRODUCT OF MAGNESIUM HALIDE, SILOXANES, ORGANIC COMPOUNDS | NIPPON OIL COMPANY, LIMITED (JP) | 1985-06-25 | — | — | US | disclosed |
| US-4405791-A | Arylthioureido pyridinecarbamino compounds and use as plant growth regulants | GULF OIL CORPORATION (US) | 1983-09-20 | — | — | US | disclosed |
| US-4292069-A | HERBICIDES | GULF OIL CORPORATION (US) | 1981-09-29 | — | — | US | disclosed |
| EP-0030789-A2 | Arylthioureido pyridinecarbamino compounds, a process for their preparation and their use as plant growth regulants | Gulf Oil Corporation (US) | 1981-06-24 | — | — | EP | disclosed |
| US-3996208-A | PENICILLINS | CIBA-GEIGY CORPORATION (US) | 1976-12-07 | — | — | US | disclosed |
| US-3964974-A | Enzymatic determination of glucose | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040048872-A1 | New derivatives of cyano-aryl (or cyanoheteroaryl) -carbonyl- piperazinyl - pyrimidines, their preparation and application as medication | CBR3, CBR1, CNR1 | KDM4E 1472/4885ALDH1A1 304/4885L3MBTL1 1773/4885 |
| US-12378254-B2 | Disubstituted octahydropyrrolo[3,4-c]pyrroles as orexin receptor modulators | HCRTR2, HCRTR1, OXTR | KDM4E 454/4885ALDH1A1 3132/4885L3MBTL1 4510/4885 |
| US-20250032473-A1 | QUINOLINE DERIVATIVES | CFTR, NQO1, IRF3 | KDM4E 2522/4885ALDH1A1 476/4885L3MBTL1 4861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.