Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | BLM | P54132 | 1/20 | 0.67 |
| ▸ | AGER | Q15109 | 1/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30503698 | 1.00 | KDM4E (0.67) | KDM4EALDH1A1L3MBTL1ALOX15TSHR | |
| SCHEMBL69990 | 0.89 | L3MBTL1 (0.62) | KDM4EALDH1A1L3MBTL1ALOX15TSHR | |
| SCHEMBL29416324 | 0.89 | L3MBTL1 (0.62) | KDM4EALDH1A1L3MBTL1ALOX15TSHR | |
| SCHEMBL2800466 | 0.86 | L3MBTL1 (0.54) | KDM4EALDH1A1L3MBTL1ALOX15TSHR | |
| SCHEMBL519094 | 0.86 | KDM4E (0.67) | KDM4EALDH1A1L3MBTL1ALOX15TSHR | |
| SCHEMBL29559479 | 0.86 | KDM4E (0.67) | KDM4EALDH1A1L3MBTL1ALOX15TSHR | |
| SCHEMBL7360329 | 0.84 | KDM4E (0.56) | KDM4EALDH1A1L3MBTL1ALOX15TSHR | |
| SCHEMBL7360249 | 0.84 | KDM4E (0.51) | KDM4EALDH1A1L3MBTL1ALOX15TSHR | |
| SCHEMBL30434883 | 0.84 | L3MBTL1 (0.53) | KDM4EALDH1A1L3MBTL1ALOX15TSHR | |
| SCHEMBL9198739 | 0.84 | L3MBTL1 (0.53) | KDM4EALDH1A1L3MBTL1ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117946186-A | Synthesis method and application of Fenton-like 5, 7-dibromo-2-methyl-8-hydroxyquinoline-bipyridyl phenazine cobalt complex | 广西医科大学 | 2024-04-30 | — | — | CN | claimed |
| US-11807886-B2 | Process for the preparation of copolymers derived from 2,4- or 2,5-pyridinedicarboxylic acid | BIOME BIOPLASTICS LIMITED (GB) | 2023-11-07 | — | — | US | claimed |
| CN-116283773-A | Sinomenine amide derivative, and preparation method and application thereof | 安徽农业大学 | 2023-06-23 | — | — | CN | claimed |
| US-20200208183-A1 | PROCESS FOR THE PREPARATION OF 2,4- OR 2,5-PYRIDINEDICARBOXYLIC ACID AND COPOLYMERS DERIVED THEREFROM | BIOME BIOPLASTICS LIMITED (GB) | 2020-07-02 | — | — | US | claimed |
| CN-109748844-A | A kind of preparation method of 2,6- dichloromethyl pyridine hydrochloride | 丹阳市宁大卫防检测技术有限公司 | 2019-05-14 | — | — | CN | claimed |
| EP-1087953-A1 | NITRATE SALTS OF ANTIHYPERTENSIVE MEDICINES | NICOX S.A. (FR) | 2001-04-04 | — | — | EP | claimed |
| WO-1999067231-A1 | NITRATE SALTS OF ANTIHYPERTENSIVE MEDICINES | NICOX S.A. (FR) | 1999-12-29 | — | — | WO | claimed |
| EP-0403627-A1 | IMIDAZOLYL AND PYRIDYL DERIVATIVES OF PHENYL SUBSTITUTED 1,4-DIHYDRO-PYRIDINES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.r.l. (IT) | 1990-12-27 | — | — | EP | claimed |
| EP-4688789-A1 | MACROCYCLIC RAS INHIBITORS | Revolution Medicines, Inc. (US) | 2026-02-11 | — | — | EP | disclosed |
| EP-4626892-A1 | ADENOSINE A2A AND A2B RECEPTOR ANTAGONISTS, PHARMACEUTICAL COMPOSITIONS AND USE THEREOF | Merck Sharp & Dohme LLC (US) | 2025-10-08 | — | — | EP | disclosed |
| US-12378254-B2 | Disubstituted octahydropyrrolo[3,4-c]pyrroles as orexin receptor modulators | JANSSEN PHARMACEUTICA NV (BE) | 2025-08-05 | — | — | US | disclosed |
| WO-2024211663-A9 | MACROCYCLIC RAS INHIBITORS | Revolution Medicines, Inc. (US) | 2025-01-30 | — | — | WO | disclosed |
| CN-116283773-B | Sinomenine amide derivative, and preparation method and application thereof | 安徽农业大学 | 2024-11-26 | — | — | CN | disclosed |
| CN-113563245-B | Substituted pyrrolidines and their use in medicine | 广东东阳光药业股份有限公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-1088927-A | Benzo and pyrido pyridazinone and pyridazinthione compounds | SYNTEX A INC (US) | 1994-07-06 | — | — | CN | disclosed |
| WO-1993007146-A1 | BENZO AND PYRIDO PYRIDAZINONE AND PYRIDAZINTHIONE COMPOUNDS WITH PDE IV INHIBITING ACTIVITY | SYNTEX (U.S.A.) INC. (US) | 1993-04-15 | — | — | WO | disclosed |
| EP-0433402-A1 | THERAPEUTIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | CELLTECH LIMITED (GB) | 1991-06-26 | — | — | EP | disclosed |
| WO-1990011769-A1 | THERAPEUTIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | CELLTECH LIMITED (GB) | 1990-10-18 | — | — | WO | disclosed |
| US-4806535-A | Imidazolylphenyl and 1,2,4-triazolylphenyl benzopyridazinone and pyridopyridazinone compounds and their use for increasing cardiatonic contractility | RORER PHARMACEUTICAL CORPORATION (US) | 1989-02-21 | — | — | US | disclosed |
| WO-1989000567-A1 | BENZOPYRIDAZINONE AND PYRIDOPYRIDAZINONE COMPOUNDS AND THEIR USE IN THE TREATMENT OF CONGESTIVE HEART FAILURE | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1989-01-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11807886-B2 | Process for the preparation of copolymers derived from 2,4- or 2,5-pyridinedicarboxylic acid | HPD, PGD, PCCA | KDM4E 378/4885ALDH1A1 326/4885L3MBTL1 4557/4885 |
| US-20200208183-A1 | PROCESS FOR THE PREPARATION OF 2,4- OR 2,5-PYRIDINEDICARBOXYLIC ACID AND COPOLYMERS DERIVED THEREFROM | HPD, PCCA, MVD | KDM4E 657/4885ALDH1A1 308/4885L3MBTL1 4344/4885 |
| US-12378254-B2 | Disubstituted octahydropyrrolo[3,4-c]pyrroles as orexin receptor modulators | HCRTR2, HCRTR1, OXTR | KDM4E 454/4885ALDH1A1 3132/4885L3MBTL1 4510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.